Replication process, occurrence

Table 3 reports the number of active compounds found in the initial screen by each design. None of the methods deviates substantially from the 76 hits expected under random sampling. The UCC designs are highly optimized hence, the two replicates have many common compounds, as shown in the last column of Table 3. The cluster-based designs choose one compound at random from each cluster there is much chance occurrence in this process and the two replicates share only about the same number of compounds as random sampling. Therefore, the random and cluster-based designs vary substantially and at least two runs are required for evaluation purposes.

It is evident from the proton-electron pair code that these tautomeric forms have the pairing scheme A -C, A-C, G -T, G-T, which means that, at a DNA replication, the tautomeric base will combine with a wrong partner. According to Watson and Crick, this process may be responsible for the occurrence of mutations. 

Replication has occurred with similarities and substantial differences The occurrence of organic matter is predicted by silica binding processes... 

Protein synthesis is essentially a translational process of messenger RNA which has been transcribed from the DNA template. The first reaction is the activation of amino acids by amino-acyl transfer RNA synthetases making use of ATP as an energy source, and the enzymes also attach the amino acid to transfer RNA to form amino-acyl transfer RNA. We have already seen that protein synthesis in plasmodia can be inhibited much further back along the chain, either at the folate co-factor level or during nucleic acid synthesis. It is obvious that interference with RNA transcription from DNA (or with DNA replication), or interference with the availability of essential amino acids, will also affect plasmodial synthesis of protein. Morphological studies of the effects of antimalarials on plasmodia support the occurrence of both modes of action for chloroquine, quinacrine, and quinine. 

Control charts The purpose of a control chart is to monitor data from an ongoing series of quantitative measurements so that the occurrence of determinate (systematic) errors (bias), or any changes in the indeterminate (random) errors affecting the precision of replicates can be detected and remedial action taken. The predominant use of control charts is for quality control (QC) in manufacturing industries where a product or intermediate is sampled and analyzed continually in a process stream or periodically from batches. They may also be used in analytical laboratories, such as those involved in clinical or environmental work, to monitor the condition of reagents, standards and instrument components, which may deteriorate over time. 

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