Renal syndromes

Pulmonary and Renal Syndrome-Hemorrhagic Fever C18-A058... 

Mixed metabolic acidosis and respiratory alkalosis occur in patients with advanced liver disease, salicylate intoxication, and pulmonary-renal syndromes. 

VHF with Renal Syndrome Asia, Europe, Worldwide Rodent Aerosol, Fomites... 

Fanconi renal syndrome (renal proximal tubule defect)... 

Hepato-renal syndrome rapid progressive (type I) with rising serum creatinine levels, or non-progressive and less severe (type II) impairment of renal function, often consequent on bacterial peritonitis, with persistent ascites responds to vasoconstrictor treatment, typically with terlipressin through constriction of splanchnic vessels and improved renal perfusion. Withdrawal of treatment does not seem to lead inevitably to recurrence. Haemodialysis may also stabilise patients. 

Figure 29.11 presents the kineties of bilirubin removal from blood plasma of eirrhotie patients with hepato-renal syndrome. In this ease, blood perfusion was... 

Amyloidosis, fatty liver, glycogenoses, Wolman s syndrome, hyperchylomicronaemia, Wilson s disease, Zellweger s cerebrohepato renal syndrome, Niemann-Pick disease, mucopolysaccharidoses, etc. 

Danks, D.M., Tippett, R, Adams, C., Campbell, R Cerebro-hepato-renal syndrome of Zellweger. J. Pediatr. 1975 86 382- 387... 

Eyssen, H., E ermont, E., van Eldere, J., Jaeken, J., Parmentier, G., Janssen, G. Bile acid abnormalities and the diagnosis of cerebro- hep-ato-renal syndrome (Zellweger s syndrome). Acta Paediatr. Scand. 1985 74 539-544... 

Mathis, R.K., Watkins, J.B., van Szczepanik-van Leeuwen, R, Lott, I.T. Liver in the cerebro-hepato-renal syndrome defective bile acid synthesis and abnormal mitochondria. Gastroenterology 1980 79 1311-1317... 

On the basis of experience in one patient and 10 published case histories, the scleroderma-pulmonary-renal syndrome, a rare and usually fatal complication of systemic sclerosis, characterized by fulminant alveolar hemorrhage and rapidly progressive renal insufficiency, has been reviewed (204). In their patient penicillamine was continued, and the disease progressed. Five of the 11 patients in their review had been using penicillamine. 

Bar J, Ehrenfeld M, Rozenman J, Perelman M, Sidi Y, Gur H. Puhnonary-renal syndrome in systemic sclerosis. Semin Arthritis Rheum 2001 30(6) 403-10. 

Lenoir GR, Perignon JL, Gubler MC, Broyer M. Valproic acid a possible cause of proximal tubular renal syndrome. J Pediatr 1981 98(3) 503-4. 

Bourgoignie JJ. Renal complications of human immunodeficiency virus type 1. Kidney international. 1990 Jun 37(6) 1571-84. RaoTK, Friedman EA. Renal syndromes in the acquired immunodeficiency syndrome (AIDS) lessons learned from analysis over 5 years. Artificial organs. 1988 Jun l 2(3) 206-9. 

Acute deterioration of renal function Salt and water retention The concept of "renal sparing" NSAIDs Nephrotic syndrome with interstitial nephritis Chronic renal failure/papillary necrosis Other NSAID-induced renal syndromes Renal effects of COX-2 inhibitors 424 428 430 431 432 434 435... 

Several renal syndromes can comphcate NSAID use [1-3, 3-5, 24]. Generally, individuals who have normal renal function and are properly hydrated, are not at risk for developing adverse renal effects [1]. NSAID-induced deterioration in renal function depends on the specific drug, the dose and duration of pharmacologic effect and the state of health of the recipient [25]. Patients who have prostaglandin-dependent states associated with co-morbid diseases, such as high renin states or chronic renal insufficiency, are especially susceptible... 

Phenylbutazone, suprofen, and benoxaprofen produce unique renal syndromes that are of historic interest. Fortunately, the use of phenylbutazone use has diminished because of the availability of safer drugs, and suprofen and benoxaprofen have been voluntarily removed from the market. 

Suprofen-induced AKI is characterized by acute flank and/or abdominal pain. In series of 16 patients. Hart et al. [114] described that the mean peak serum creatinine was 3.6 mg/dl (range 2 to 8 mg/dl), which returned to normal limits at follow-up. Suprofen is know to have uricosuric activity leading Hart and colleagues [114] to suggest that this renal syndrome may have resulted from ureteral or tubular precipitation of uric acid. 

Risk factors have been identified for most NSAID-induced renal syndromes (Table 3). It is prudent to avoid high-dose, chronic NSAID therapy in patients... 

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