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Relevance of PPARa Activator-Induced Rodent Liver Tumor Response to Humans

RELEVANCE OF PPARa ACTIVATOR-INDUCED RODENT LIVER TUMOR RESPONSE TO HUMANS  [Pg.467]

Abdellatif, A. G., Preat, V., Vamecq, J., Nilsson, R., and Roberfroid, M. (1990). Peroxisome proliferation and modulation of rat liver carcinogenesis by 2,4-dichlorophenoxyacetic acid, 2,4,5-trichlorophenoxy-acetic acid, perfluorooctanoic acid and nafenopin. Carcinogenesis 11, 1899-1902. [Pg.467]

Anderson, S. P, Dunn, C. S., Cattley, R. C., and Gorton, 1. G. (2001). Hepatocellular proliferation in response to a peroxisome prohferator does not require TNFalpha signaling. Carcinogenesis 22, 1843-1851. [Pg.467]

Anderson, S. R, Howroyd, P., Liu, J., Qian, X., Bahnemann, R., Swanson, C., Kwak, M. K., Kensler, T. W., and Corton, J. C. (2004b). The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes. J Biot Chem 279, 52390-52398. [Pg.468]

Arsura, M., and Cavin, L. G. (2005). Nuclear factor-kappaB and liver carcinogenesis. Cancer Lett 229, 157-169. [Pg.468]




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Human activities

Human liver

Human response

Human tumor

Humans PPARa activation

Liver activities

Liver inducible

PPARa

Responses to activation

Rodent

Tumors, liver

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