Sensors refractometric

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Xu, F. Horak, P. Brambilla, G., Optical microfiber coil resonator refractometric sensor, Opt. Express 2007, 15, 7888 7893... 

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Zamora, V. Diez, A. Andres, M. V. Gimeno, B., Refractometric sensor based on whispering gallery modes of thin capillaries, Opt. Express 2007, 15, 12011 12016... 

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A chemical sensor is a device that transforms chemical information into an analytically useful signal. Chemical sensors contain two basic functional units a receptor part and a transducer part. The receptor part is usually a sensitive layer, therefore a well founded knowledge about the mechanism of interaction of the analytes of interest and the selected sensitive layer has to be achieved. Various optical methods have been exploited in chemical sensors to transform the spectral information into useful signals which can be interpreted as chemical information about the analytes [1]. These are either reflectometric or refractometric methods. Optical sensors based on reflectometry are reflectometric interference spectroscopy (RIfS) [2] and ellipsometry [3,4], Evanescent field techniques, which are sensitive to changes in the refractive index, open a wide variety of optical detection principles [5] such as surface plasmon resonance spectroscopy (SPR) [6—8], Mach-Zehnder interferometer [9], Young interferometer [10], grating coupler [11] or resonant mirror [12] devices. All these optical... 

Fig. 112. Affinity sensor for dehydrogenases using refractometric indication. (Redrawn from Mandenius et al., 1986).

Refractometric sensitivity describes the sensitivity of the SPR sensor to refractive index n and can be written as ... 

The (dynamic) range describes the span of the values of the measurand that can be measured by the sensor. In refractometric SPR sensors the dynamic range usually describes a range of values of the refractive index of the sample that can be measured with a specified accuracy. Dynamic range of SPR biosensors defines the range of concentrations of an analyte which can be measured with specified accuracy and extends from the lowest concen-... 

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