Reference sequence

Fig. 3.7.2 DDIF (1) and reference (2) scan pulse sequences. The tipping angles of the pulses are marked as jt and jt/2. te and tD are two time periods. An echo signal is detected for DDIF and an FID for the reference sequence. Phase cycling of rf pulses is shown in Tables 3.7.1 and 3.7.2.

Polymorphic variant A gene, mRNA, cDNA, polypeptide or peptide whose nucleotide or amino acid sequence varies from a reference sequence due to the presence of a polymorphism in the gene. 

Format 1 SBH can be used to uncover polymorphism and mutations in a particular gene. The sample amplicons of genomic DNA of a test individual and the amplicons for the control DNA for the gene of interest with a known reference sequence are both prepared by polymerase chain reaction (PCR). A subset of probes that is complementary... 

Comparative sequence analysis based on MALDI-TOF-MS analysis of nucleic acids cleaved at specific bases and reference sequences used to construct in silico cleavage patterns enable cross-correlation of theoretical and experimental mass signal patterns. Observed signal pattern differences are indicators of sequence variations and... 

Reference sequences. GPCRDB (http //www.gpcr.org/7tm/) and NCBI (http //www.ncbi.nlm.nih.gov/), SwissProt/ TrEMBL (http //www.expasy.org/sprot/). 

Coordinates, numbered according to the Cambridge Reference Sequence (62, 63). 

RefSeq (Reference Sequences) e CDD (Conserved Domain Database)... 

Reference sequences of chromosomes, genomic contigs. mRNAs. and proteins for human and major model organisms... 

Submit the following sequence to structure prediction by the multiple alignment of the query sequence with the reference sequences of proteins whose 3D structures are known in Joy sequence/structure representation. 

Amino acid sequence comparison of a-glucan phosphorylases. H, the potato type-H isozyme L, the potato type-L isozyme and R, rabbit muscle phosphotylase.791 The type-H isozyme sequence is used as the reference sequence only the amino acid residues that are nonidentical in the type-L isozyme and rabbit muscle enzyme are indicated. (From Biol. Chem., 266 (28), 18453 (1991)). 

The optimal composition of a FISH probe mixture for detection of changes in gene copy number in solid tumors includes two labeled probes. One probe directed towards the gene of interest and one probe directed towards a reference sequence for the chromosome on which the target gene is located. Traditionally, the reference probes are directed towards the non-coding centromere sequences. 

Figure 1. Example of a FISH probe mixture. A 291 kb long Texas Red-labeled probe directed towards MYC and a fluorescein-labeled probe towards CEN-8 reference sequences on the same chromosome.

Figure 24. Local shape of value landscapes. Selective values as defined by Eqs. (IV.9)-(IV.ll) of 70 nearest neighbors surrounding a given reference sequence Ig are shown. Upper curve refers to evaluation according to third model for g = 1 as in Figure 22. Middle curve represents free energies according to second model evaluation. Lower curve counts numbers of base pairs in different folding patterns Free energy follows approximately number of base pairs, but excess production shows roughly opposite trend.

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