Redox stress

Heiss EH, Schilder YD, Dirsch VM. 2007. Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells. J Biol Chem 282 26759-26766. 

We now examine specific features of core metabolism, and its reductive pathways in particular, as augmented relaxation channels for redox stress. We begin with... 

Lander. H. M.. Ogiste, J. S., Teng, K. K., and Novogrodsky, A. (1995), p2lras a.s a common. signaling target of reactive free radicals and cellular redox stress. 7. Biol. Chem. 270,21195-21198. 

Goldkom, T. et al., EGF-receptor phosphorylation and signaling are targeted by H202 redox stress, Hw. J. Respir. Cell Mol Biol, 19,786, 1998. 

Lander HM, Ogiste JS, Teng KK, Novogrodsky A. p21ras as a common signaling target of reactive fiee radicals and cellular redox stress. J Biol Chem 1995 270(36) 21195-21198. 

Hayden, M.R. and Tyagi, S.C. 2004. Neural redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic neuropathy. Medical science monitor, 70 RA291-RA307. 

Initially Pd salts were used as homogeneous catalysts dissolved in the reaction media. However, the redox stress due to the oxidative addition and reductive elimination steps in the general mechanism (see Scheme 2.16) causes agglomeration of Pd° atoms into less catalytically active NPs that grows in size during the reaction becoming completely deactivated due to the large final dimensions. 

Electrochemical corrosion is understood to include all corrosion processes that can be influenced electrically. This is the case for all the types of corrosion described in this handbook and means that data on corrosion velocities (e.g., removal rate, penetration rate in pitting corrosion, or rate of pit formation, time to failure of stressed specimens in stress corrosion) are dependent on the potential U [5]. Potential can be altered by chemical action (influence of a redox system) or by electrical factors (electric currents), thereby reducing or enhancing the corrosion. Thus exact knowledge of the dependence of corrosion on potential is the basic hypothesis for the concept of electrochemical corrosion protection processes. 

If cellular redox state, determined by the glutathione status of the heart, plays a role in the modulation of ion transporter activity in cardiac tissue, it is important to identify possible mechanisms by which these effects are mediated. Protein S-,thiolation is a process that was originally used to describe the formation of adducts of proteins with low molecular thiols such as glutathione (Miller etal., 1990). In view of the significant alterations of cardiac glutathione status (GSH and GSSG) and ion-transporter activity during oxidant stress, the process of S-thiolation may be responsible for modifications of protein structure and function. 

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