Redox sensing

Fe Bacteria/Archaea Electron transport/ Redox sensing [Pe3S,] [Pe,S,T -140 to -460 52... 

Remarkable work by Frangois Diederich of the ETH lab in Zurich has resulted in the buckminster-fullerene-based redox sensing device 15.7. This novel sensor, which is produced in yields of up to 50 per cent, holds a dibenzo [18] crown-6 cavity in enforced close contact with the fullerene surface. Binding of K+ within the crown ether cavity results in relatively large anodic shifts of 90 mV of the first fullerene reduction (C60 C60 ). The implication is that the proximity of the potassium cation to the fullerene... 

There is a wider general interest in understanding the oxidation of cysteine thiolates in proteins since they are involved in redox-sensing reactions [99], Therefore, such oxidation reactions of thiols induced by Ru coordination may also play a more general role in the pharmacological activity of Ru-arene complexes by coupling Ru coordinative binding to redox processes both outside and inside cells. 

The electrode is a combination probe containing a platinum (redox) sensing element and an iodine-sensing reference element. The potential developed at the platinum element depends upon the relative levels of iodine and iodine ion in solution ... 

Zheng, M. and G. Storz. Redox sensing by prokaryotic transcription factors. Biochem. Pharmacol. 59 1-6, 1999. 

Oxidation of receptor 1 was found to decrease its binding affinity for alkali metal cations, due to electrostatic repulsion between 1 and the cation. Thus, the ferrocene unit not only enables redox sensing of alkali metal cations, but also allows the host guest interaction to be switched on and off depending on the oxidation state of the receptor. Saji has also demonstrated that this phenomenon can be used in electrochemical ion transport across liquid membranes. ... 

Helmann JD. OxyR a molecular code for redox sensing . Sci STKE 2002 2002 PE46. 

Key words Halorhodospira halophila, Ectothiorhodospira, Elalobacterium salinarum, Rhodobacter sphaeroides, Synechocystis, Rhodocista centenaria, Rhodospirillum centenum. Swimming motility, Swarming motility. Twitching motility. Photoactive yellow protein, Sensory rhodopsin, Phytochrome, BLUF, Redox sensing... 

Szemes, F. Anion recognition and redox sensing amplification by self-assembled monolayers of 1,1 -i>A(alkyl-N-amido)ferrocene. Chem. Commun. 2002, 1716-1717. 132. 

The transcriptional repressor Rex is a redox-sensing protein playing a role in the shift from acidogenesis to solventogenesis in C. acetobutylicum [102]. Rex controls the expression of butanol biosynthetic genes in response to NADH/NAD" ratio in the cell [102,103]. Rex is also present in C. beijerinckii [103] and in C. saccharobutylicum as well as C. saccharoperbutylacetonicum (BLAST analysis using JGI/IMG website). 

Wietzke, M. and Bahl, H. (2012) The redox-sensing protein Rex, a transcriptional regulator of solventogenesis in Clostridium acetobutylicum. Appl. Microbiol. Biotechnol, 96, 749-761. 

Genereux JC, Boal AK, Barton JK. DNA-mediated charge transport in redox sensing and signaling. J Am Chem Soc. 2010 132 891-905. 

As redox sensing is one of the ways to activate the Nrf2/Keapl pathway, reactive oxygen species or H2O2, but also electrophilic compounds such as tert-butyl-hydroquinone or oltipraz and numerous natural compounds present in fruits or vegetables such as suUbraphane (Kensler et al. 2013), curcumin, resveratrol, pteros-tilbene (Ramkumar et al. 2013) are known to induce the transcription of Nrf2 target... 

The use of SAMs for investigating the binding properties of redox-active groups at a surface has been explored over the past few years by a number of research groups as described in various reviews. Some examples of redox-active receptors that form monolayers and respond electrochemically to complexation are shown in Figures 10 and 11 (compounds 53-58). Dendrimers and nanoparticle-coated monolayers for various applications including redox sensing have attracted considerable attention over the last... 

This is particularly interesting because aldehydes (Chapter 9), lying (in a redox sense) between primary alcohols and carboxylic acids, are generally too labile to be isolated in the presence of oxidizing agents. Indeed, as will be encountered later (Chapter 9), many aldehydes spontaneously oxidize (in the presence of air) to the corresponding carboxylic acids. 

Ornelas C, Aranzaes JR, Salmon L, Astruc D (2008) Click dendrimers synthesis, redox sensing of Pd(OAc)(2), and remarkable catalytic hydrogenation activity of precise Pd nanoparticles stabilized by 1,2,3-triazole-containing dendrimers. Chemistry 14 50... 

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