Recognition event

Section 25 16 Carbohydrates and proteins that are connected by a chemical bond are called glycoproteins and often occur on the surfaces of cells They play an impor tant role m the recognition events connected with the immune response... 

Explain how the ion-recognition event is translated to the response of the corresponding ISE. 

Prasanna de Silva A, Gunaratne H.Q.N., Gunnlaugsson T., Huxley A.J.M., McCoy C.P., Rademacher J.T., Rice T.E., Signaling Recognition Events with Fluorescent Sensors and Switches, Chem. Rev. 1997 97 1515 (review). 

The tuneable nature of the evanescent field penetration depth is critical to the effective operation of this sensor as it facilitates surface-specific excitation of fluorescence. This means that only those fluorophores attached to the surface via the antibody-antigen-labelled antibody recognition event... 

T. Sakata and Y. Miyahara, Detection of DNA recognition events using multi-well field effect devices. Biosens. Bioelectron. 21, 827-832 (2005). 

This diverse set of biosensing experimental demonstrations illustrates the flexibility of the OFRR device. Nearly any biomolecular recognition event can be detected. The examples illustrated with the previously described experiments include DNA sequence detection and virus detection through surface proteins. Additional biosensing examples for which the OFRR is well-suited include site-specific cleavage, protein-protein interactions, and cell genotype/phenotype identification through receptors. Furthermore, as shown by the theory outlined above, the OFRR can be accurately and precisely quantitative. 

The macrocydic polyether dibenzo[24]crown-8 (DB24C8, Scheme 3) binds124,251 dialkylammonium-containing guests in solution, as well as in the solid state, to generate complexes with pseudorotaxane co-conformations that are stabilized primarily by [0—H-N+] and [O —H-C] hydrogen bonds. The com-plexation and decomplexation kinetics of these recognition events are influenced by the size of the... 

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