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Receptor-mediated response

Recombinant systems can also be engineered to produce receptor-mediated responses by introducing adjunct proteins. For example, it has been shown that the Gal6 G-protein subunit couples universally to nearly all... [Pg.85]

Horii Y, Khim JS, Higley EB, Giesy JP, Ohura T, Kannan K (2009) Relative potencies of individual chlorinated and brominated polycyclic aromatic hydrocarbons for induction of aryl hydrocarbon receptor-mediated responses. Environ Sci Technol 43(6) 2159-2165. doi 10.102 l/es8030402... [Pg.311]

Sergeeva, O. A., Eriksson, K. S. Haas, H. L. (2001). Glycine receptor mediated responses in rat histaminergic neurons. Neurosci. Lett. 300, 5-8. [Pg.175]

Subchronic studies that measure Ah receptor-mediated responses, such as thymic atrophy, loss in body weight, and immunotoxicity... [Pg.1244]

Patemain, A. V., Morales, M., and Lerma, J. (1995) Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons. Neuron 14,185-189. [Pg.42]

Bureau, I., Bischoff, S., Heinemann, S. F., and Mulle, C. (1999) Kainate receptor-mediated responses in the CA1 held of wild-type and GluR6-dehcient mice. J. Neurosci. 19, 653-663... [Pg.46]

Hampson AJ, Bornheim LM, Scanziani M, Yost CS, Gray AT, Hansen BM, Leonoudakis DJ, Bickler PE. (1998). Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. J Neurochem. 70(2) 671-6. [Pg.523]

Martin G, Nie Z, Siggins GR. (1997). mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons. J Neurosci. 17(1) 11-22. [Pg.526]

Banu Y. Watanabe T Augmentation of antigen receptor-mediated responses by histamine Hj receptor signaling. J Exp Med 1999 189 673-682. [Pg.79]

The Role of Second Messengers in Receptor-mediated Responses... [Pg.98]

At therapeutic doses, the first- and second-generation antihistamines are equilibrium-competitive inhibitors of Hi-receptor-mediated responses. Certain second-generation drugs are noncompetitive inhibitors at high concentrations. Both first- and second-generation compounds have negligible abilities to block the H2-, H3-, or H4-receptors. The therapeutic effectiveness of these... [Pg.453]

We demonstrated for the first time that crocin selectively antagonizes the inhibitory effect of ethanol on NMDA-receptor-mediated responses in hippocampal neurons. This action of crocin may underlie the antagonism against ethanol-induced memory impairment. Crocin should be useful as a new pharmacological tool for studying the mechanism of ethanol inhibition of NMDA receptor functions. [Pg.326]

Herrero, J. F., Headley, P. M., Parsons, C. G. Mementine selectively depresses NMDA receptor-mediated responses of rat spinal neurones in vivo, Neurosci. Lett. 1994, 165, 37-40. [Pg.418]

This means that there is a spectrum of degree to which a receptor can be stimulated (Fig. 3 — 14). At one end of the spectrum, there is the full agonist, which elicits the same degree of physiologic receptor-mediated response as the natural neurotransmitter agonist itself. At the other end of the spectrum is a full inverse agonist, which in concept does the opposite of the agonist. In the middle is the... [Pg.85]

Dunwiddie TV, Diao L, Kim HO, Jiang JL, Jacobson KA (1997) Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptor-mediated responses in rat hippocampus. J Neurosci 17(2) 607-614... [Pg.183]

The results suggest that alprazolam modulates peripheral concentrations of dehydroepiandrosterone and that dehydroepiandrosterone and/or dehydroepiandrosterone-S may have an in vivo role in modulating GABA receptor-mediated responses. [Pg.574]

The primary uses of adrenergic agonists and antagonists according to their selectivity for individual receptor subtypes are summarized in Table 20-1. In general, a specific agonist is used to mimic or increase the receptor-mediated response, whereas the antagonist is used to decrease the receptor-mediated response. [Pg.274]

Chapter 6 Introduction to Autonomic Pharmacology). The -receptor-mediated response is probably of greater pharmacologic significance than the B-stimulant response. Alpha2 receptors may also decrease salt and water flux into the lumen of the intestine. [Pg.185]

Connor, K., J. Howell, I. Chen, H. Liu, K. Berhane, C. Sciarretta, S. Safe, and T. Zacharewski (1996). Failure of chloro-.v-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro. Fund. Appl. Toxicol., 30 93-101. [Pg.409]

Tran, D.Q., J.A. McLachlan, and S.F. Arnold (1996). The inhibition of estrogen receptor-mediated responses by chloro-s-triazine-derived compounds is dependent on estradiol concentration in yeast. Biochem. Biophys. Res. Comm., 227 140-146. [Pg.411]

O Kane EM, Stone TW (1998) Interaction between adenosine Ai and A2 receptor-mediated responses in the rat hippocampus in vitro. Eur J Pharmacol 362 17-25 Ohkubo S, Kimura J, Matsuoka I (2000) Ecto-alkaline phosphatase in NG108-15 cells a key enzyme mediating PI antagonist sensitive ATP response. Br J Pharmacol 131 1667-2 Okada M, Mizuno K, Kaneko S (1996) Adenosine Ai and A2 receptors modulate extracellular dopamine levels in rat striatum. Neurosci Lett 212 53-6 Okada M, Nutt DJ, Murakami T et al (2001) Adenosine receptor subtypes modulate two major functional pathways for hippocampal serotonin release. J Neurosci 21 628 40 Oliveira L, Correia-de-Sd P (2005) Protein kinase A and Cavl (L-Type) channels are common targets to facilitatory adenosine A2a and muscarinic Mj receptors on rat motoneurons. Neurosignals 14 262-72... [Pg.368]

Other studies further indicated that PCBs may antagonize Ah receptor-mediated responses to... [Pg.346]


See other pages where Receptor-mediated response is mentioned: [Pg.541]    [Pg.105]    [Pg.247]    [Pg.1178]    [Pg.329]    [Pg.72]    [Pg.216]    [Pg.94]    [Pg.355]    [Pg.277]    [Pg.315]    [Pg.86]    [Pg.263]    [Pg.110]    [Pg.77]    [Pg.255]    [Pg.968]    [Pg.50]    [Pg.31]    [Pg.35]    [Pg.185]    [Pg.389]    [Pg.268]    [Pg.270]    [Pg.463]   
See also in sourсe #XX -- [ Pg.50 ]




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