Reasoned Alternatives

The shear viscosity is a tensor quantity, with components T] y, t],cz, T)yx> Vyz> Vzx> Vzy If property of the whole sample rather than of individual atoms and so cannot be calculat< with the same accuracy as the self-diffusion coefficient. For a homogeneous fluid the cor ponents of the shear viscosity should all be equal and so the statistical error can be reducf by averaging over the six components. An estimate of the precision of the calculation c then be determined by evaluating the standard deviation of these components from tl average. Unfortunately, Equation (7.89) cannot be directly used in periodic systems, evi if the positions have been unfolded, because the unfolded distance between two particl may not correspond to the distance of the minimum image that is used to calculate the fore For this reason alternative approaches are required. 

Have reasonable alternatives for each component been identified ... 

Reid (1976) and many other authors give pure propane a superheat temperature limit of 53 C at atmospheric pressure. The superheat temperature limit calculated from the Van der Waals equation is 38°C, whereas the value calculated from the Redlich-Kwong equation is S8°C. These values indicate that, though an exact equation among P, V, and 7 in the superheat liquid region is not known, the Redlich-Kwong equation of state is a reasonable alternative. 

A reasonable alternative to the PDLD method can be obtained by approaches that represent the solvent as a dielectric continuum and evaluate the electric field in the system by discretized continuum approaches (see Ref. 15). Note, however, that the early macroscopic studies (including the... 

Disulfiram inhibits CYP enzymes 1A2, 2C9, and 3A4 many benzodiazepines are metabolized via these pathways lorazepam, temazepam, and oxazepam are NOT metabolized via the CYP4S0 system and are reasonable alternatives. 

NSAIDs are a reasonable alternative when acetaminophen fails to provide an acceptable analgesic response. Some authorities recommend NSAIDs over acetaminophen for patients presenting with severe pain or signs and symptoms of inflammation, but this is a matter of much contention. The rationale for this recommendation is that acetaminophen s central mechanism of action renders it ineffective against peripheral joint inflammation, and therefore, less effective.18 Consensus guidelines support the use of NSAIDs as an alternative to acetaminophen if clinical features of peripheral inflammation or severe pain are detected.11,12 Unfortunately there is no validated mechanism to identify patients who are more likely to respond to NSAIDs than acetaminophen. 

However, an equally reasonable alternative was proposed in which both species are identified as Fe(C0)4 with different geometries (53). 

Decide that slowing down the kinetics by temperature lowering is not a reasonable alternative. 

Luminescence spectroscopy provides simple access to the splitting of the ground multiplet but this technique is not always accessible due to nonradiative decay and strong ligand absorptions as encountered, for example, in the [Ln(Pc)]-/0 systems. For these reasons, alternative spectroscopic tools should be available for magnetochemists. The use of INS as a spectroscopic probe for molecular magnetic systems has recently been reviewed by Guidi [36], Amoretti et al. [37]... 

Type III hyperlipoproteinemia may be treated with fibrates or niacin. Although fibrates have been suggested as the drugs of choice, niacin is a reasonable alternative because of the lack of data supporting a cardiovascular mortality benefit from fibrates and because of their potentially serious adverse effects. Fish oil supplementation may be an alternative therapy. 

Chronic hypertension is defined as elevated BP that was noted before pregnancy began. Methyldopa is considered the drug of choice because of experience with its use. /3-Blockers, labetalol, and CCBs are also reasonable alternatives. ACE inhibitors and ARBs are known teratogens and are absolutely contraindicated. The direct renin inhibitor aliskiren also should not be used in pregnancy. 

Oral mesalamine derivatives (such as those listed in Table 26-5) are reasonable alternatives to sulfasalazine for treatment of ulcerative colitis but they are not more effective than sulfasalazine. 

Rectal administration is a reasonable alternative in patients in whom oral or parenteral administration is not feasible. 

Amoxicillin-clavulanate is the agent of choice for oral outpatient treatment however, this agent does not cover P. aeruginosa. Fluoroquinolones with metronidazole or clindamycin are reasonable alternatives. 

A detailed analysis published for fuel-cell drive systems by Schirrmeister et al. (2002) showed a specific cost breakdown of the added value of a fuel-cell drive system powered by methanol (a methanol reformer was a reasonable alternative at that time)... 

Other eluent systems in suppressed ion chromatography are typically chosen based on specific separation requirements. For routine analysis of monovalent and divalent anions, carbonate-based eluents represent a reasonable alternative to hydroxide-based eluent systems. Carbonate eluents are simple to prepare and can be useful in cases where anion analysis is only occasionally performed. It must be kept in mind, however, that carbonate lowers the detection sensitivity for anionic species and introduces significant nonlinearity into the analysis. ... 

As in any classification problem, there is a tradeoff between the rate of recall, or proportion of correct substructures detected, and the reliability, or avoidance of false positive assertions. It is rather the exception than the rule for an observation to have a single, unequivocal explanation. When reasonable alternative interpretations are possible, a decision must be made about what to report. At one extreme, all possibilities could be asserted, ensuring 100% recall (i.e. no substructure which is actually present will fail to be detected) at the cost of a high rate of false positives. 

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