Signal analyzers, real time

The spectral region of interest is then detected and processed by means of an optical multichannel analyzer (EG G-PARC model 1215, OMA). The OMA detector SIT (silicon intensified target), EG G-PARC model 1254 has been used. It is operated by the detector controller, EG G-PARC, model 1216, which performs the signal digitization as well. The acquired spectra are displayed in real time on a TV display and on the OMA console. The data storage and processing are also performed by that console which has a 28K of 16 bit core memory and a floppy disk for permanent storage. 

In a recent publication, the largest number of AD brains to date were analyzed by microarray. Unlike the previous studies, the RNA from 61 AD frontal cortex samples and 53 controls samples were pooled, and multiple hybridization experiments took place on two-array platforms. Only 3 of the top 30 differentially expressed genes from each platform were found to be in common RGS4 and RAB3A were decreased and ITPKB was increased. However, real-time PCR with the individual samples confirmed these changes were specific to the AD patients, and these data support the evidence of disrupted intracellular calcium signaling in AD [112],... 

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