Rash, renal impairment

Adverse effects of ACE inhibitors include hypotension, dizziness, headache, fatigue, GI disturbances, bad taste in the mouth, persistent dry cough, skin rashes, renal impairment, hypokalemia, and blood disorders. ACE inhibitors also can cause chest pain, palpitation, tachycardia, abdominal pain, cholestatic jaundice, alopecia, mood and sleep disturbances, and impotence. 

Administration may result in nausea, vomiting, diarrhea, rash, anemia, leukopenia, and thrombocytopenia Signs of renal impairment include elevated blood urea nitrogen (BUN) and serum creatinine levels. Periodic renal function tests are usually performed during therapy. 

Oral allopurinol (Zyloprim ) Adult 600-800 mg/day in 2-3 divided doses Child 10 mg/kg per day or 200-300 mg/m2 per day Adult 200-400 mg/m2 per day Child 200 mg/m2 per day 0.48/day (generic) Adjust dose for renal impairment. Avoid drug interactions (mercaptopurine). Monitor for skin rash. 

Adverse reactions may include renal impairment hearing loss neutropenia vertigo dizziness anaphylaxis drug fever nausea chills eosinophilia rashes hypotension wheezing dyspnea urticaria inflammation at injection site Red Man (or Redneck) syndrome chemical peritonitis has been reported following intraperitoneal... 

Action Monobactam, -1- cell wall S5mth Dose Adul. 1—2 g IV/EM q6-12h Peds. Premature 30 mg/kg/dose IV ql2h Term children 30 mg/kg/dose q6-8h X in renal impair Caution [B, +] Disp Inj SE NA /D, rash, pain at inj site Interac tions T Effects W/probenecid, aminoglycosides, i-lactam antibiotics X effects W7 cefoxitin, chloramphenicol, imipenem EMS Monitor for S/Sxs of super Infxn may cause aUCTgic Rxns rare cross-sensitivity Rxns to penicillins and cephalosporins have been rqwrted OD May cause Szs symptomatic and supportive... 

Ciprofloxacin (Cipro, Cipro XR, Proquin XR) [Antibiotic/ Fluoroquinolone] Uses Rx lower resp tract, sinuses, skin skin structure, bone/joints, urinary tract Infxns including prostatitis Action Quinolone antibiotic DNA gyrase Dose Adults. 250-750 mg PO ql2h XR 500-1000 mg PO q24h or 200-400 mg IV ql2h in renal impair Caution [C, /-] Children <18 y Contra Component sensitivity Disp Tabs, susp, inj SE Restlessness, N/V/D, rash, ruptured tendons, T LFTs Interactions T Effects Wf probenecid T effects OF diazepam, theophylline, caffeine, metoprolol, propranolol, phenytoin, warfarin effects W/ antacids, didanosine, Fe salts. Mg, sucralfate, Na bicarbonate,... 

Minocycline (Solodyn) [Antibiotic/Tetracycline] Uses Acne Action Tetracycline, bactmostatic Dose Adults Peds >12 y. 1 mg/kg PO daily X 12wk w/ food to -1- irritation Caution [C, ] assoc w/ pseudomembranous colitis w/ renal impair Contra AU gy, women of childbearing potential Disp Tabs SE D, HA, fevCT, rash, joint pain, fatigue, dizziness Interactions t Effects OF digoxin, oral anticoagulants t risk of n hrotox W/ methoxyflurane X effects W/... 

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