Rapacuronium bromide

Molecular formula C37H6iBrN204 Molecular weight 677.81 CAS Registry No 156137-99-4 Merck Index 13,8201 

Matrix bile, blood, stoma fluid, tissue, urine 

Mobile phase Dioxaneibuffer 16 84 (Caution Dioxane is a carcinogen ) (The buffer was 100 mM sodium dihydrogen phosphate containing 0.11 mM 9,10-dimethoxyanthracene-2-sutfonate and 0.11 mM 1-heptanesulfonic acid, pH adjnsted to 3.0 with orthophos-phoric acid. After each series of analyses, flush column with 15 mL water and 75 mL MeOH.) 

Detector F ex 385 em 452 following post-column extraction. The column effluent mixed with dichloroethane pumped at 1 mL/min and the mixture flowed through a 1 m x 0.25 mm ID stainless steel coil to a phase separator (Organon International) and then the organic phase flowed through the detector (J.Chromatogr. 1987, 421, 327 Anal.Chim.Acta 1987,192, 267). 

Internal standard l-(3o , 17/3-dihydroxy-2/S-morpholino-5o -androstan- 16/3-yl)- 1-meth-ylpiperidinium bromide (Org 7402, Organon) (21) 

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Rapacuronium bromide Raplon Organon Anesthetic, muscle relaxant 9/19/1999 3/30/2001 7 months Bronchospasm 23 million... 

Szenohradszky J, Caldwell JE, Wright PM, Brown R, Lau M, Luks AM, Fisher DM. Influence of renal failure on the pharmacokinetics and neuromuscular effects of a single dose of rapacuronium bromide. Anesthesiology 1999 90(l) 24-35. 

Raji B-cell lymphoma 526 RANTES 363 Rapl 43 Rap Ip 42 3 Rapacuronium bromide 52 Rapamune 1538... 

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