Raffinose crystal structure

F. Alberto, E. Jordi, B. Henrissat, and M. Czjzek, Crystal structure of inactivated Thermotoga maritima invertase in complex with the trisaccharide substrate raffinose, Biochem. J., 395 (2006) 4574-62. 

Many drugs and excipients (cephalexin monohydrate, quinidine sulfate dihydrate, ampicillin trihydrate, codeine sulfate trihydrate, morphine sulfate dihydrate, dicalcium phosphate trihydrate, raffinose pentahy-drate, lactose monohydrate) utilize water as an integral part of their crystal structure. Solids that form specific crystal hydrates tend to sorb relatively small amounts of water to their external surface below a characteristic relative humidity, when initially dried to an anhydrous... 

Berman, HM. The crystal structure of a trisaccharaide, raffinose pentahydrate. Acta Crystallogr 1970 B26 290—299. 

Jeffrey GA, Huang D. The hydrogen bonding in the crystal structure of raffinose pentahydrate. Carbohydr Res 1990 206 173-182. 

Table 4. Comparison of the NMR-Derived Raffinose Angles across the Glycosidic Linkages with Those Derived from the Crystal Structure. There are clear deviations for both linkages, the Glc-Fru being more pronounced.

D-galactose, C HiiOe. Crystallizes in the pyranose form m.p. 1I8-120 C (monohydrate), 165-5" C (anhydrous). An isomer of glucose which is fairly widely distributed in plants. It is a constituent of raffinose and slachyose, of hemicelluloses, of pectin, of gums and mucilages, and of some glycosides. In animals it forms half the lactose molecule and is the sugar found in the brain. Chemically it is very similar to glucose. It has the structure... 

Considering these problems, we tested a computer extrapolation (6) for sucrose, shown in the conformation maps in Figure 4. Four sets of crystal parameters were used, those from the structure of sucrose (S) (45) and those from the sucrose component of raffinose pentahydrate... 

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