Raffinose pentahydrate

Ci8H32016 5 H20 0-a-D-Galactopyranosyl-(l- 6)-0-a-D-glucopyranosyl /J-D-fructofuranoside, pentahydrate (raffinose, pentahydrate) RAFINO 30 455... 

Considering these problems, we tested a computer extrapolation (6) for sucrose, shown in the conformation maps in Figure 4. Four sets of crystal parameters were used, those from the structure of sucrose (S) (45) and those from the sucrose component of raffinose pentahydrate... 

Raffinose pentahydrate has interesting infinite chains of hydrogen bonds. The hydrogen-bonding pattern is composed of four infinite chains, three of which extend in the direction of the crystallographic axes as shown in Fig. 13.59. These chains intersect at the water molecules to form an ordered homodromic network. The five water molecules are linked together. Four are double acceptors and one (W1) is a single acceptor [507 a]. 

RAFINO. Raffinose pentahydrate [C18H32016, (5(H20)]. Berman HM (1970) Acta Crystallogr, Sect B 26 290... 

Excipient D-(- -)-Raffinose pentahydrate Manufacturer Sigma-Aldrich (Lot No. 092K01211) Magnification lOOx... 

Berman, HM. The crystal structure of a trisaccharaide, raffinose pentahydrate. Acta Crystallogr 1970 B26 290—299. 

Acros Organics N.V. Material Safety Data Sheet. No 93702 D-Raffinose pentahydrate, 2 August 2000. 

MDL Information Systems, Inc. Material Safety Data Sheet D-Raffinose pentahydrate, 22 March 2001. 

Jeffrey GA, Huang D. The hydrogen bonding in the crystal structure of raffinose pentahydrate. Carbohydr Res 1990 206 173-182. 

Raman spectra of raffinose pentahydrate following exposure to an atmosphere of D2O vapor (approximately 75% RH). The OD stretching peak increases with time and can be integrated to monitor the kinetics of the exchange process. 

Crystal packing diagram for raffinose pentahydrate. Three of the water molecules are located in a channel (Wl, W2, and W4) and two are located outside of the channel (W3 and W5). For clarity, only the oxygen molecules of the water are shown at 50% of the van der Waals radii. (Source Reproduced from Ahlqvist, M.U.A. and Taylor, L.S. Water diffusion in hydrated crystalline and amorphous sugars monitored using H/D exchange, /. Pharm. Sci., 91, 690-698, 2002. With permission of the copyright owner.)... 

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