Quinolines 8-hydroxy-, methylation

Hydroxy-containing polymers such as poly(methyl-methacrylate-co-hydroxyethyl methacrylate) [65,66] or secondary cellulose acetate [67,68] were used for this purpose. Vanadium (V) 8-hydroxy quinoline-hydroxy-ethyl methacrylate adduct, prepared by condensation of the latter with a VOQ2OH complex, is polymerized to... 

Quinoline, 8-mercapto-2-methyl-metal complexes, 2, 800 Quinoline, 2-methyl-8-(methylthio)-metal complexes, 2,801 Quinoline, 8-methylthio-metal complexes, 2, 801 Quinoline-2-carboxylic-acid, 8-hydroxy-methyl ester... 

Quinaldohydroxamic acid as metal precipitant, 506 Quinodimethane, tetracyano-metal complexes, 263 Quinoline, 8-(alkylthio)-metal complexes, 801 Quinoline, 8-hydroxy-metal complexes, 795 Quinoline, 8-hydroxy-2-methyl-cobalt(II) complexes, 795 Quinoline, 8-mercapto-metal complexes, 800 Quinoline, 8-mercapto-2-methyl-metal complexes, 800 Quinoline, 2-methyl-8-(methylthio)-metal complexes, 801 Quinoline, 8-methylthio-metal complexes, 801 8-Quinolineselenol metal complexes, 807 Quinones... 

AminosuIfonyl-l-hydroxy- IX, 607 -1-sulfonhydroxamsaure X/4, 216 Phthalimid N-(Methylthio-metho-xy)- El6a, 231 (O-Alkyl.) Quinolin 2-Methyl-3-sulfo- E7a, 332 (2-NH2 —Ar —CHO + H3C-CO-CH2-SOjH) Thieno(2,3-c]pyridin 5-Ethoxycarbo-nyl-7-hydroxy- E16c, 122 (aus En-azid/Ringschl.) Thieno(3,2-c]pyridin 6-Ethoxycarbo-nyl-4-hydroxy- E16c, 122 (aus En-azid/Ringschl.)... 

Step G 4-[Ortho-(2, 3 -Dihydroxypropyloxycarbonyl)-Phenyl]-Amino-S-Trifluoromethyl-quinoline Acetonide - 100 cc of toluene were added to 80 cc of 2,2-dimethyl-4-hydroxy-methyl-1,3-dioxolane and the toluene was distilled off under reduced pressure to eliminate the water present. To the anhydrous 2,2-dimethyl-4-hydroxymethyl-1,3-dioxolane thus obtained, 0.25 gram of an oily 50% suspension of sodium hydride and then 21.3 grams of 4-... 

Recently kinetic data have become available for the nitration in sulphuric acid of some of these hydroxy compounds (table 10.3). For 4-hydroxyquinoline and 4-methoxyquinoline the results verify the early conclusions regarding the nature of the substrate being nitrated in sulphuric acid. Plots of log Q against — (Lf + logioflHao) fo " these compounds and for i-methyl-4-quinolone have slopes of i-o, i-o and 0-97 at 25 C respectively, in accord with nitration via the majority species ( 8.2) which is in each case the corresponding cation of the type (iv). At a given acidity the similarity of the observed second-order rate constants for the nitrations of the quinolones and 4-methoxy-quinoline at 25 °C supports the view that similarly constructed cations are involved. Application of the encounter criterion eliminates the possibilities of a... 

H-Cyclopenta[7,8]naphtho[2,3-6]furan-7-yl glyoxylate, 2,3,6,10-tetrahydro-6-hydroxy-6-methyl-3,10-dioxo-, methyl ester H NMR. 4, 560 (66JCS(C)743) Cyclopenta[6]quinoline, 6,7,8,9-tetrahydro- C NMR, 2, 122 (77JOC300, 77JOC2742)... 

Quinoline, amino-2-hydroxy-4-methyl-azo pigments from, 1, 334 Quinoline, 8-amino-6-methoxy-as antimalarial, 2, 517 Quinoline, 4-amino-2-methyl-protonation, 2, 341 Quinoline, anilino-3-substituted... 

Quinoline-4-carboxylic acid, 3-hydroxy-Pfitzinger synthesis, 2, 446 Quinoline-4-carboxylic acid, 2-methyl-synthesis, 2, 475... 

Ultraviolet spectra have long been used to study systems of this type. In 1889, comparison of the ultraviolet spectrum of 2-hydroxy-quinoline with those of its O- and A -methylated derivatives led... 

On boiling the methiodide with 70% sulfuric acid an N-methyl-oxo derivative was obtained, and this in turn gave 3-amino-2-phenyl-quinoline, methylamine, and ammonia on fusion with soda lime. The bulk of the evidence therefore favors quaternization at N-2 (cf, 154), in which case the acid-hydrolysis product is 155. Quaternization at N-2 would be expected because of the steric influence of the 10-phenyl group and the influence of the 4-amino group (cf. 4-hydroxy-pyridazine ) in the pyridazine-type ring, although the partial double-bond character of that ring is probably different from that in pyridazine itself. 

In this connection the conversion of 8-hydroxy quinoline to 1-methyl-8-hydroxyquinolinium betaine (91)should also be men-... 

Reaction of 2,3-dihydro-3-hydroxy-3-methyl- 240 (R = Me), or a mixture of 2,3-dihydro-3-hydroxy-3-aryl-57/-pyrido[l,2,3-dfe]-l,4-benzoxazin-5-ones 240 (R = Ar) and (8-aroylmethoxy)quinolin-2(l//)-ones 241 (R = Ar) with ethyl 2-(bromomethyl)acrylate in the presence of activated Zn and hydroquinone gave 8-[(2,3,4,5-tetrahydro-4-methylidene-5-oxo-2-furanyl)-methoxy]quinolin-2(l//)-ones (242) (97HCA1161). 6,7-Dihydro derivatives of 240 reacted similarly (00HCA349). 

Quinaldine (2-methyl-quinoline) (2) 2-methyl-4(lH)-quinolinone (3) 3 -hydroxy-2-methyl-4( 1 H)quinolinone (4) N-acetylanthranilic acid (5) Anthranilic acid (6) Catechol (1) Quinoline (2) 2(lH)quinolinone (3) 8-hydroxy-2(lH)quinolinone (4) 8-hydroxycoumarin (5) 2, 3-dihydroxyphenylpropionic acid... 

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