Quaternary ammonium compounds, bacterial

Biocides probably have multiple target sites on viral particles and the overall damage caused results in loss of viral infectivity (Table 5.1). When compared to bacterial cells, however, viruses present only a few structural targets to biocides the envelope (when present), the glycoproteins, the capsid and the nucleic acid. The activity of biocides against the viral envelope has not been well documented but it can be expected that membrane-active agents such as phenolics and the cationic biocides (e.g. chlorhexidine and quaternary ammonium compounds — Q ACs) will act against the viral envelope, which is a typical unit membrane. The capsid is... 

Obviously, not all predicted transporters are being confirmed to be polyspecific, but quite a few of them are [15], underscoring the impressive scale of the bacterial "resistome. We should consider ourselves lucky that not all of these polyspecific transporters, frequently dubbed MDRs, are in fact clinically relevant. While they effectively expel dyes, quaternary ammonium compounds, and other organic... 

In order to prevent the development of tolerances or resistances of the pathogens to the disinfectants, a regular change of the disinfectants is highly desirable. The aetive ingredients of surface disinfeetants are aldehydes (II, 2.), quaternary ammonium compounds (II, 18.1.), and phenolics (II, 7.). Alcohols can only be used for the disinfection of small areas due to the risk of explosions. The bacterial spores ought to be destroyed by peroxygen compounds, such as the peracetic add (El, 21.1.). 

Quaternary ammonium compounds, which interfere with the bacterial cell membrane these are very little used in plastics although a few are used as fungicides. 

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