Quantitative structure-activity relationship standard deviation

Quantitative structure—activity relationships have been established using the Hansch multiparameter approach (14). For rat antigoiter activities (AG), the following (eq. 1) was found, where, as in statistical regression equations, n = number of compounds, r = regression coefficient, and s = standard deviation... 

McFarland JW, Berger CM, Froshauer SA, Hayashi SF, Hecker SJ, Jaynes BH, Jefson MR, Kamicker BJ, Lipinski CA, Lundy KM, Reese CP and Vu CB, Quantitative Structure-activity relationships among macrolide antibacterial agents In vitro and in vivo potency against Pasteurella multocida, /. Med. Chem., 40, 1340-1346 (1997). NB See Azithromycin for details average standard deviation of 0.07 for the pKa value. 

QSAR = quantitative structure-activity relationship SASA = solvent-accessible surface area SD = standard deviation SE = standard error. 

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