Quantitative and Qualitative Process Elements

Accelerated Development Strategy Objective Focus Analysis Features 

Quantitative process approach High throughput analysis Sample volume Provide increased support when a go decision is made for development. Increased resources and/or improved methods of analysis. Independent of sample generation. Intralaboratory integration (i.e., automation). 

Qualitative process approach Elimination of weak candidates Pharmaceutical properties Generate information to stop development. Development of a new application and implemented during early stages of development. Integrated with sample generation. Interlaboratory integration (i.e., predictive models). 

Source Courtesy of Milestone Development Services, Newtown, Pa., U.S.A. 

Refinement approaches lead to a decreased cycle time via the faster and more efficient analysis of samples. Automation is an obvious and desirable goal to speed up the analysis, optimize the measurement, and coordinate diverse tasks. A tremendous emphasis is placed on aspects of analysis such as sample preparation and data processing and data management. Once considered to be peripheral to the actual analysis, these activities have become important elements of high throughput analysis. 

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