QSY 21 CARBOXYLIC ACID SUCCINIMIDYL ESTER

Imaging/Labeling Applications Nucleic acids cells oligonucleotides avidin trastuzumab bacteria spores cathepsin G-protein-coupled mPT Pc is mi/ rr rgajjisms proteins,  

Biological/Medical Applications Ruorescence quencher detecting nucleic acids,  

Handbook of Fluorescent Dyes and Probes, First Edition. R. W. Sabnis. 

Sabnis, R. W. Handbook of Biological Dyes and Stains John Wiley Sons Inc. Hoboken, 2010 pp 393-395. 

Haugland, R. R Singer, V. L. Yue, S. T. Xanthene dyes and their application as luminescence quenching compounds. PCT Int. Appl. WO 2000064988, 2000. 

Solubility Soluble in dimethyl sulfoxide, methanol Melting Point 200 °C Absorption ( max) 560 nm Synthesis Synthetic methods  

CA Index Name Xanthylium, 9-[2-[[4-[[(2,5-dioxo-l-pyrrolidinyl)oxy]carbonyl]-l-piperidinyl]sulfonyl]phe-nyl]-3,6-bis(methylphenylamino)-, chloride (1 1) Other Names Xanthylium, 9-[2-[[4-[[(2,5-dioxo-l-pyrrolidinyl)oxy]carbonyl]-l-piperidinyl]sulfonyl]phe-nyl]-3,6-bis(methylphenylamino)-, chloride QSY 7 carboxylic acid succinimidyl ester QSY 7SE QSY-7 succi-nimidyl ester 

Merck Index Number Not listed Chemical/Dye Class Xanthene Molecular Formula C43H39CIN4O7S Molecular Weight 791.32 

Staining Applications Nucleic acids oligonucleotides bacteria peptides tumors  

Biological Applications Amplification assays hybridization assays litigation assays FRET assays hepatitis C virus (HCV) NS3 protease FRET 

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