Pyrrole 3 - carboxy - 2 - methyl - 4 -

Carbomethoxybenzaldehyde, 30, 100 5-Carbomethoxy valeryl chloride, 38, 39 Carbon disulfide, 30, 57 39, 8, 78 Carbonic acid, trithio-, bis(carboxy-methyl) ester, 39, 77 Carbonic-carboxylic anhydrides, 37, 21 Carbon monoxide, 34, 14 Carbon oxysulfide, 32, 103 Carbon tetrachloride, 32, 27 37, 8 Carbonylation, of pyrogallol-1,3-dimethyl ether with hexamethylenetetramine, 31, 92 of pyrrole with dimethylformamide,... 

Figure 5.26 Variation of anodic peak potential ( pa vs SCE) of poly(3-carboxy-methyl pyrrole) as a function of pH determined by cyclic voltammetry at 25 mV/s. (Reprinted from New Journal of Chemistry, 15, D. Delabouglise, F. Gamier, 233.

PBG synthase (EC 4.2.1.24) acts on two equivalents of 5-aminolevulinate to produce the condensation product, prophobilinogen (PBG) [5-(aminomethyl)-4-(carboxy-methyl)-lH-pyrrole-3-propanoic acid] and two equivalents of water (Scheme 14.26). The pathway has been examined in some detail and it appears that imines are formed with two separate lysine residues. The imines undergo condensation. ... 

Elektronenreiche Carboxy-N-heteroarene erleichtern ebenfalls die Hydrogenolyse (anwesende Alkoxycarbonyl- bzw. Formyl- oder Acyl-Gruppen werden mitreduziert). Pyrrol-carbonsauren werden z. B. durch Lithiumalanat in Diathylather oder THF zu den entsprechenden Methyl-pyrrolen reduziert4 s z, B.4 ... 

The benzene ring has been proposed as an isosteric replacement in a dipeptide to enforce either the tram l1 1 or the cis conformation 312>31 (Scheme 1). Similarly, 2-(amino-methyl)pyrrole-l-acetic acid (8, R = H) has been proposed as a cis peptide bond mimic,141 having the same number of atoms between the amino and carboxylic acid functions as in a dipeptide. Several other amino- and carboxy-substituted aromatic structures have been used as spacers in peptides 2-, 3-, and 4-aminobenzoic acids (Abz, e.g., 7), 2-, 3-, and 4-(amino-methyl)benzoic acids (Amb, e.g., 2), 2-, 3-, and 4-(aminophenyl)acetic acids (APha, e.g., 5), 2- (4), 3-, and 4-(aminomethylphenyl)acetic acid (Ampa), (aminomethyl)pyrrole-, -thiophene-, and -furancarboxylic acids 6, (aminomethyl)pyrrole- 8 and -thienylacetic acids, and aminobiphenylcarboxylic acids. 

Pyridin 4-Carboxy-3-hydroxy-5-hy-droxymethyl-2-methyl- IV/lb, 548 Pyrrol 3,4-Dimethoxycarbonyl-E6a, 653 (Ar —S02 —CH2 —NC + ROOC - CH=CH - COOR),... 

Pyrrol 3-Carboxy-2-(4,4-dimethyl-4,5-dihydro-l,3-oxazol-2-yl)-l-methyl- E6a, 748 (H - Li - COOH)... 

IH-[Pg.1154]

C9H11N04 3-carboxy-1,4-dimethyl-1 H-pyrrole-2-aceticac 33369-45-8 557.68 49.452 2 17115 C9H120 4-methyl-3-ethyl phenol 6161-67-7 509.15 47.490 1,2... 

It is usually assumed that the mechanism of chemical polymerization is similar to that described earlier in electropolymerization. However, work in our own laboratories71 highlights the fact that it is difficult to duplicate the products of electropolymerization using a chemical oxidant. Studies using 3-methyl-4-carboxy-pyrrole have demonstrated that polymers obtained with both techniques are similar in chemical composition but differ markedly with respect to polymer morphology. 

C.G. Overberger, K.-H. Davidu. J.A. Moore, Macromolecules5, 368 (1972) die untersuchte Verbindung, 2-Carboxy-5-methyl-3,4-dihydro-2H-pyrrol, wurde auf einem anderen Weg hergestellt. 

Tb2 ] Bromination of 2-formylpyrrole and methyl pyrrole-2-carboxy-late occurs at the 4-, 5-, and 4,5-positions387. 

To 5a] In view of the behaviour of esters of pyrrole-dicarboxylic acids, already reported, it is interesting to notice that methyl pyrrole-2-carboxy-late undergoes alkaline hydrolysis considerably faster than the 3-isomer [10 A 2 (1. mole i sec ) (25°), 231, 4 1 and 0 59, for ethyl pyrrole-1-, and methyl pyrrole-2- and -3-carboxylate, respectively, in 56 per cent aqueous acetone]. The effect is attributed to intramolecular hydrogen bonding in the transition state (109)374 (cf. to c above). 

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