Pymetrozine

Chloral chloretoxyfos, chloralose, DDT, dichlorvos, dicofol, methoxychlor, naled, plifenate, trichlamide, trichlorfon, triforine Chlordane heptachlor Chlordene chlordane Chlorine cyanide see cyanogen chloride Chloro acetaldehyde nipyraclofen, oxabetrinil Chloro acetone pymetrozine Chloro acetonitrile thicyofen... 

Hydrazine bisthiosemi, clethodim, clofentezine, diclomazine, difenzoquat, ferimzone, flupoxam, maleic hydrazide, metamitron, methidathion, metribuzin, pymetrozine, tebuthiuron, thiazafluron, triclopyr Hydrazine (acetyl) metamitron Hydrazine (tertiobutyl) tebufenozide Hydrazine (p.tertio butyl benzyl) pyridaben Hydrazine (2.4 dichloro phenyl) sulfentrazone Hydrazine (dimethyl) daminozide Hydrazine (2.6 dimethyl phenyl) oxadixyl... 

Oxadiazole (5 trifluoro methyl 2-3H one) pymetrozine Oxalic acid cycloprothrin... 

In homopterans, pymetrozine prevents insects from inserting their stylus into plant tissue. The feeding disruption appears to be related to the nervous regulation of feeding behavior that consequently results in death due to starvation (Harrewijn and Kayser, 1997). Its oral LD50 in rats is >5000 mg/kg. 

Harrewijn, P. and Kayser, H., Pymetrozine, a fast-acting and selective inhibitor of aphid feeding. In-situ studies with electronic monitoring of feeding behaviour, Pestic. Sci., 49,130,1997. 

Kayser, H., Kaufmann, L. and Schurmann, F. (1994) Pymetrozine (CGA 215 944) a novel compound for aphid and whitefly control. An overview of its mode of action. Brighton Crop Protection Conference - Pests and Diseases, 2, 737-742. 

The recoveries of the acid-labile pesticides ethoxy quin and pymetrozine can be raised if 1.5 g of trisodium citrate is used, instead of using 1 g of the di- and... 

Pymetrozine (1 developmental code CGA 215 944) is an insecticide, highly active and specific against sucking pests. It is the only commercial representative of the chemical class of the pyridine azomethines. Pymetrozine is marketed by Syngenta under the trademarks of Chess , Plenum, Fulfill , Relay , and Sterling [1-4]. 

Pymetrozine (1), a pyridine azomethine, was synthesized for the first time at the end of 1986 [3, 5]. The concept behind this discovery was primarily chemically directed with, however, a strong rational element [2j. In a first step ring transformations of 1,3,4 oxadiazolon-3-yl ketones 2 with N-nucleophiles were investigated, leading to numerous new five- and six-membered N-amino heterocydes,... 

An economical route has been developed for the preparation of pymetrozine (1) (Scheme 30.1.2). The last step is quite remarkable In a one-pot procedure pyridine-3-carbonitriIe is converted into 3-pyridine aldehyde by a catalytic hydrogenation and subsequently condensed with 4-amino-6-methyl-4,5-dihydro-l,2,4-triazin-3(2H)-one to give pymetrozine in high yields [2, 5, 14-16]. 

Selective Feeding Blockers (Pymetrozine, Flonicamid) 1091 Table 30.1.1 Key inventions related to the chemical class of the pyridine azomethines. 

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