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Putterlickia verrucosa

A Streptomyces strain isolated from Brazilian (Maytenus aquifolia) and South African (Putterlickia retrospinosa, Putterlickia verrucosa) plants has furnished celastramycin A (1212) (1225). A new isomer of the known rumbrin ( ) was isolated from an Australian soil ascomycete, Gymnoascus reessii, and named (12 ,)-isorumbrin (1213) (1226). Somewhat earlier, the three related auxarconju-gatins A, B, and (3 Z)-A (1214-1216) were characterized from an Arizona soil microorganism Auxarthron conjugatum (1227). A basidiomycete fungus from a New Zealand forest, Chamonixia pachydermis, produces pachydermin (1217) (1228). [Pg.182]

Maytenus ovatus, M. senata [fruit] Putterlickia verrucosa [wood] (Celastraceae)... [Pg.388]

Maytansines Maytenus serrata i Maytenus buchananii > (Celastraceae) Putterlickia verrucosa Colubrina texensis (Rhamnaceae) Antimitotic, antileukaemic, antitumour... [Pg.32]

Colubrina texensis Graj (Rhamnaceae) Putterlickia verrucosa S sjl (Celastraceae) Putterlickia verrucosa Scjsjl (Celastraceae) Majtenus serrata (Celastraceae)... [Pg.491]

The crystal and molecular structure and the absolute configuration of maytansine (73) were studied using its 3-bromopropyl ether [121] and the cytotoxicity of 73 [122] was reported. Several other maytansinoids, such as colubrinol (74), normaytancyprine (75) [123], 10-epitrewiasine (76), trewiasine (77) and nortrewiasine (78) [124], were isolated from Putterlickia verrucosa and Trewia nudiflora, respectively, and the structure elucidation, and the structural requirements for antileukemic activity of natural and semisynthetic maytansinoids were reported [120, 125]. As described above, maytansine (73) was isolated initially from a higher plant, although it was evident that the content of this compound was extremely low. [Pg.70]

Two new maytansinoids, maytanacine (228) and maytansinol (229), were isolated from the alcoholic extract of the stem of Putterlickia verrucosa Szyszyl. [260], the richest reported source of maytansine (218) and related antileukemic esters. Maytanacine (228), which exhibited... [Pg.724]

Sneden AT, Sumner WC Jr, Kupchan SM 1982 Normaytancyprine, minor antileukemic ansa macrolide from Putterlickia verrucosa. J Nat Prod 45 624-628... [Pg.1156]

See other pages where Putterlickia verrucosa is mentioned: [Pg.826]    [Pg.491]    [Pg.491]    [Pg.504]    [Pg.826]    [Pg.480]    [Pg.695]    [Pg.1108]    [Pg.1108]    [Pg.826]    [Pg.491]    [Pg.491]    [Pg.504]    [Pg.826]    [Pg.480]    [Pg.695]    [Pg.1108]    [Pg.1108]   
See also in sourсe #XX -- [ Pg.23 , Pg.70 ]

See also in sourсe #XX -- [ Pg.70 ]

See also in sourсe #XX -- [ Pg.695 ]



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