Putrescine synthesis

PULSE-CHASE EXPERIMENTS N-END RULE PULSE RADIOLYSIS PURINE NUCLEOSIDASE PURINE NUCLEOSIDE PHOSPHORYLASE PUTRESCINE CARBAMOYLTRANSEERASE PUTRESCINE N-METHYLTRANSEERASE PUTRESCINE OXIDASE Putrescine synthesis,... 

In plants, the profile of adc and ode gene expression is tissue dependent and changes in different processes such as cell division, cell proliferation or stress responses [104-105]. Thus, adc and ode transcripts were preferentially expressed in roots and floral tissue of mature tobacco plants [106]. Besides, in Glycine max main roots and hypocotyls vascular buddle, ode and adc genes are co-localized [107]. Moreover, it is suggested that in apple cells ADC rather than ODC is the primary pathway for putrescine biosynthesis [108], while others authors suggest that ODC is much more important than ADC for putrescine synthesis in rice [109]. 

Guan JJ et al (2004) Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester) triblock copolymers and putrescine synthesis, characterization and cytocompatibility. Biomaterials 25(l) 85-96... 

Which of the following drugs is an antimetabolite that inhibits a trypanosomal enzyme involved in putrescine synthesis ... 

The induction of cinnamoyl putrescine accumulation in phosphate-depleted tobacco cells is maximal when inorganic nitrogen is supplied (37). This is not surprising since nitrogen is a component of the HCA precursors Phe and putrescine. However, the fact that ammonium citrate is much more effective than KNO in the induction of cinnamoyl putrescine synthesis in... 

Berlin and Witte (89) have determined that PAL, rather than substrate supply, is most important in regulating cinnamoyl putrescine synthesis in tobacco cell cultures. 

The residue of crystalline putrescine dihydrochloride is rinsed onto a Buchner funnel with the aid of 100-200 ml. of absolute ethanol used in several portions. The last portions of ethanol are used as wash liquid for the crystals. The crystals are finally pressed dry and washed with 25 ml. of ether. The air-dried product weighs 53-55 g. (72-74%) and melts above 275. Analysis for chlorine indicates that the salt is anhydrous. Concentration of the filtrate to a volume of about 25 ml. yields an additional 1-2 g. total yield 73-77%. The entire synthesis may be completed in one day. 

Arginine is the formamidine donor for creatine synthesis (Figure 31-6) and via ornithine to putrescine, spermine, and spermidine (Figure 31-3) Arginine is also the precursor of the intercellular signaling molecule ni-... 

Figure 31-3. Arginine, ornithine, and proline metabolism. Reactions with solid arrows all occur in mammalian tissues. Putrescine and spermine synthesis occurs in both mammals and bacteria. Arginine phosphate of invertebrate muscle functions as a phosphagen analogous to creatine phosphate of mammalian muscle (see Figure 31-6).

The synthesis of alkaloids from L-ornithine starts with decarboxylation by the Pyridoxal Phosphate (PLP) to putrescine (Figure 33) and putrescine metylation by 5 -Adenosylmethionine (SAMe) to A-methylputrescine. The SAM is a naturally occurring reaction, when the departing groups convert... 

Figure 33. Synthesis of alkaloids from ornithine. Aikaioids are derived via putrescine or glutamic semialdehyde. At least two enzymes, ODL (Ornithine decarboxylase) or PDL (Pyrroline...

The synthesis of tropine from tropinione requires dehydrogenase NADPH+. Similarly, the synthesis of cocaine requires the Mannich reaction, SAM and NADPH+. Putrescine is a biogenic amine. Other biogenic amines also participate in alkaloid synthesis, for example cadaverine in the case of lysine alkaloids. Aniszewski et al. " drew attention to the fact that the various biogenic amines... 

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