Purification of Fatty Acid Amides Using Urea

Purification of Fatty Acid Amides Using Urea [Pg.117]

The natural fatty acid amides are mixtures of saturated fatty acid amides and unsaturated fatty acid amides. The present invention is based on the fact that the unsaturated fatty acid amides can be isolated very easily from a mixture of fatty acid amides by treating the fatty acid amides with urea or thiourea. The unsaturated fatty acid amides have more effective biological activity. [Pg.117]

To 10 parts by weight of hot cyclohexyl amides of fatty acids of safflower oil (iodine value, 90), is added a hot solution of 5 parts of urea in 10 parts of methanol, simultaneously with vigorous stirring and the mixture is allowed to stand at room temperature for 24 hours. After the separated crystals are removed by filtration, the filtrate is treated with water and extracted with ether. The extract is washed with water, dried and concentrated to give the objective material having an iodine value of 140. Source Sumitomo Chemical Co. 1967 [Pg.117]

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