Protium kleinii antinociceptive effect

The production of pro-inflammatory substances is an important step during chronic painful inflammatory diseases and its inhibition is a target of novel analgesics. The resin of Protium kleinii is used in folk medicine for inflammatory skin conditions. Its effects seem to be mediated by several pentacyclic triterpenes such as amyrin and brein [92], The topical and systemic administration of the extract of P. kleinii and some of its triterpenes has antinociceptive and anti-inflammatory actions, accompanied by reduced neutrophil infiltration and cytokine... 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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