Proteomics networks

Administrative Optimization of Proteomics Networks for Drug Development... 

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Janes, K. A. and Lauffenburger, D. A. 2006. A biological approach to computational models of proteomic networks. Curr Opin Chem Biol, 10,73-80. 

Waters KM, Shankaran H, Wiley HS, Resat H, Thrall BD. Integration of microarray and proteomics data for biological pathway analysis and network modeling of epidermal growth factor signaling in human mammary epithelial cells. Keystone Symposia, 2005. 

Zhang H,Tang X, Munske GR, et al. In vivo identification of the outer membrane protein OmcA-MtrC interaction network in Shewanella oneidensis MR-1 cells using novel hydrophobic chemical cross-linkers. J. Proteome Res. 2008 7 1712-1720. 

Guerrero C, Tagwerker C, Kaiser P, et al. An integrated mass spectrometry-based proteomic approach quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network. Mol. Cell. Proteomics. 2006 5 366-378. 

A. J. Pocklington, M. Cumiskey, J. D. Armstrong, and S. G. N. Grant. 2006, The Proteomes of Neurotransmitter Receptor Complexes from Modular Networks with Distributed Functionality Underlying Plasticity and Behaviour, www.molecularsystemsbiology.com—Article nr 2006.0023. 

W. Liebermeister and E. Klipp, Bringing metabolic networks to life Integration of kinetic, metabolic, and proteomic data. Theor. Biol. Med Modeling 3(42), (2006). 

The application of the improved MS techniques presented above with highly resolving separation methods, such as 2-D electrophoresis, capillary HPLC, and CE, resulted in the creation of a new science, proteomics63 While genomics, described by DNA databases, represents the ground stage of the cell, the study of the differential status of the cell, due to various stimuli or disease states, reflects the functional expression of protein products or proteomics. Proteomics studies are aimed at identifying the proteome, the network of proteins that define the... 

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