Proteolysis technological applications

We demonstrated that proteic and/or carbohydrate coating can render an enzyme less susceptible to thermal denaturation, enzymatic proteolysis and immunological attack. Carbohydrates or proteins can also be fixed in order to target the enzyme to the right tissue(s) or cell(s). Little is still known about the in vivo behaviour of such molecular associations but the promises of enzyme technology for therapeutic applications (lysosomal storage diseases for instance) are so great as to stimulate such studies in the near future. 

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