Proteoglycans lungs

There are other glycosaminoglycans. Hyaluronic acid [9004-61-9] occurs both free and in noncovalent association with proteoglycan molecules. Heparin [9005-49-6] and heparan sulfate [39403-40-2] also known as heparitin sulfate [9050-30-0] occur in mast cells and in the aorta, Hver, and lungs. 

Heparan sulfate consists of the repeating disaccharide /3-D-glucopyranosyluronic acid-(1 4)-iV-sulfato-2-amino-2-deoxy-a-D-glucopyranosyl linked (1 4). This polysaccharide is linked to a core protein to give a proteoglycan that is found as a matrix component of arterial wall, lung, heart, liver, and skin [93]. 

Stevens, R.L., Fox, C.C., Lichtenstein, L.M. and Austen, K.F. (1988b). Identification of chondroitin sulfate E proteoglycans and heparin proteoglycans in the secretory granules of human lung mast cells. Proc. Natl. Acad. Sci. USA 85, 2284-2287. 

Hernnas, J., Sarnstrand, B., Lindroth, P., Peterson, C.G.P., Venge, P. and Malmstrdm, A. (1992). Eosinophil cationic protein alters proteoglycan metabolism in human lung fibroblasts. Eur. J. Cell Biol. 59, 352-363. 

Even in healthy lungs, collagen is the most abundant component of the lung interstitium (elastin and proteoglycan being the other primary compo-... 

CM. Further characterization of a large proteoglycan in human lung alveoli. Eur J Cell Biol 1986 39 386-390. 

Bensadoun ES, Burke AK, Hogg JC, Roberts CR. Proteoglycans in granulomatous lung diseases. Eur Respir J 1997 10 2731-2737. 

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