3- propenoyl acids

Typical procedure for the cyclization of f-(aryltelluro)propenoyl acids with P2O . 7-Methoxy-4-oxo-4H-l-benzotellurinP 2-Carboxyethenyl 3-methoxyphenyl tellurium (1.20 g, 3.92 mmol) is added to a solution of 1 g of phosphorus pentoxide in 10 mL of distilled methanesulphonic acid and the resultant mixture is stirred at 20°C for 4 h. Saturated aqueous sodium hydrogen carbonate solution (250 mL) is then added dropwise, the mixture is extracted with three 50 mL portions of dichloromethane and the combined extracts are dried with anhydrous sodium sulphate, fdtered and concentrated. The residue is recrystallized from methanol. Tield 0.76 g (67%) m.p.l03°C. 

Phenyl-2-propenoic acid, e279 3-Phenyl-2-propen-l-ol, c282 3-Phenyl-2-propenoyl chloride, c280 3-Phenylpropyl alcohol, pi46 Phenyl propyl ketone, b619... 

The 4-0X0-477-1-benzoteUurins have also been prepared by the cyclization of 2-(3-dimethylamino propenoyl)-phenyl tellurenyl bromide by heating with hypophosphorous acid in pyridine. ... 

Oriamide (441), a cytotoxic peptide containing the unusual amino acid, 4-propenoyl-2-tyrosylthiazole, was isolated from a Theonella sp. from South Africa [367]. Theonella cupola from Indonesia and from... 

Phenylthiotrimethylsilane adds to propenoyl trimethylsilane under the influence of Lewis acid to give l,3-bis(phenylthio)-l-trimethylsilylprop-l-ene (18). This enol thioether may be deprotonated with f-butyl lithium and alkylated with any of a large range of electrophiles. Subsequent hydrolysis-elimination with mercuric chloride in aqueous acetonitrile provides -substituted a,/J-unsaturated acyl silanes (vide supra, Section III.D.3)132. It should be noted that, in this transformation, the /1-substituent has... 

Boc group of 44, followed by the condensation of the resultant amine with 3-ethoxy-2-propenoyl isocyanate, afforded urea 45. The cyclization of 45 with sulfuric acid and the subsequent removal of the benzoyl group gave thionucleoside 46. Nucleoside 46 was further converted to thionucleoside 47. Meanwhile, gem-difluorohomoallyl alcohol 49, which was derived from (S)-glyceraldehyde acetonide 48 and 3-bromo-3,3-difluoropro-pene, was converted to thionucleosides 50a and 50b by applying the same strategy [13]. Thionucleosides 50a and 50b were further converted to thionucleosides 51a and 51b (see Scheme 8.7). 

Cinnamic acid chloride Cinnamic chloride Cinnamoyl chloride EINECS 203-065-5 NSC 4683 p-Phenylactyloyl chloride 3-Phenyl-2-propenoyl chloride 2-Propenoyl chloride, 3-phenyl-. Reagent for determination of small amounts of water, chemical intermediate. Yellow crystals mp = 36° bp = 257°, bp2 = 101° d = 1.1617 very soluble in ligroin. ICI Spec. Janssen Chimica LatKaster Synthesis Co. Penta Mfg. Pfalz Bauer. 

An important feature of the utility of bis(trimethylsilyl) hypophosphite in synthesis consists in its capability to undergo addition reactions, and which has been exploited in several ways to provide phosphinic acids which possess carboxy groups these reactions are summarized in Scheme 40 (the structures indicated here represent the final products following the acidolytic removal of trimethylsilyl groups). An equimolar mixture of phenylphosphonous dichloride (PhPCl2) and phenylphosphonous acid (phenylphosphinic acid) behaves as the phosphinic chloride 434, and so adds across carbonyl activated carbon-carbon multiple bonds by virtue of the presence of the P—H bond propenoyl chloride thus affords the acid dichloride 435, which may be hydrolysed to 3-(hydroxyphenylphos-phinoyl)propanoic acid (436). ... 

Di-2-propenoyl-2,2-dimethyl-1,3-propanediol 2-Propenoic acid, 2,2-dimethyl-1,3-propanediyl ester C11H16O4 2223-82-7 212.243 1.4642 ... 

Di-2-propenoyl-1,6-hexanediol 2-Propenoic acid, 1,6-hexanediyl ester C12H19O4 13048-33-4 226.269 1.010 ... 

Epoxyfuranoeremophilane-3,6-diol 3-(2-Methyl-2-propenoyl), 6-Ac, in E-10085 12-Methoxy-6,11,14-trioxo-8,12-abietadien-18-oic acid, in H-10237 Tinophyllol, in E-10101... 

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