1 -Methoxy-1 - propene

Propen 2-Methoxy-3-oxo-3-phenyl-E15/1, 209 (Enol-ether + R-Li/R-COOH)... 

Chemically, wood tar is a complex mixture that contains at least 200 individual compounds, among which the foUowing have been isolated (1) 2-methoxyphenol, 2-methoxy-4-ethylphenol, 5-meth5i-2-methoxyphenol, 2,6-x5ienol, butyric acid, crotonic acid, 1-hydroxy-2-propanone, butyrolactone, 2-methyl-3-hydroxy-4JT-pyran-4-one, 2-methyl-2-propenal, methyl ethyl ketone, methyl isopropyl ketone, methyl furyl ketone, and 2-hydroxy-3-methyl-2-cyclopenten-l-one. 

Coniferyl aicohol [4-hydroxy-3-methoxy-cinnamyl alcohol, 3-(4-hydroxy-3-methoxy-phenyl)-2-propen-l-ol] [458-35-5] M 180.2, m 73-75°, b 163-165°/3mm, pK 9.54. It is... 

It was elaimed that eyelization of ethyl 2-ehloro-5-eyelopropyl-6- [(A-(4,5-dimethoxy-2-nitrophenyl)methoxy)earbonyl]-A-(2-fluoro-3-hydroxy-l-oxo-2-propen-l-yl)amino nieotinate (321) in boiling aqueous dioxane in the presenee of K2CO3 overnight yielded l- [(4,5-dimethoxy-2-nitrophe-nyl)methoxy]earbonyl -9-eyelopropyl-3-fluoro-2-oxo-2,6-dihydropyrido[l, 2-n]pyrimidine-7-earboxylate (160) (95MIP1, 96MIP4, 96USP5580872). 

Chelation control, as indicated in 5, is also a suitable model for rationalizing the stereochemical outcome of titanium tetrachloride mediated additions of 3,3-dimelhyl-2-trimethylsilyl-oxy-l-butenc (6) or l-methoxy-2-methyl-l-trimethylsilyloxy-l-propene (7) to 3-benzyloxy-2-methylpropanal (4). In both cases, there is almost exclusive formation of the chelate-controlled product (95 5 and >97 3, respectively)13. 

The Lilanium(lV) chloride mediated reactions of the silylketene acetal, l-methoxy-2-methyI-l-trimethylsilyloxy-l-propene. with a-methylthioaldehydes afford predominantly adducts resulting from chelation control, besides minor amounts of the diastereomers10. 

Schwer reduzierbare kon jugierte Nitro-olefine, z. B. phenolische 2-Nitro-1-phenyl-propen-Derivate, werden zweckmaBig mit Natrium-bis-[2-methoxy-athoxy]-di-hydrido-aluminat zu den 2-Amino-1 -phenyl-propanen umgesetzt12 ... 

Dagegen wird 3-Methoxy-3-phenyI-propin in Dimethylformamid/Tetrabutylammo-niumjodid an Quecksilber (-2,3 V) quantitativ zu 3-Methoxy-3-phenyl-propen reduziert1. 

Jacobsen and co-workers14 have shown that a tridentate Schiff base chromium complex 13 catalyzed an asymmetric carbonyl-ene reaction between a variety of aryl aldehydes (14, Equation (8)) and 2-methoxy propene 15 or 2-trimethylsiloxypropene. The highest yields were afforded when the aryl ring was substituted with an electron-withdrawing group however, the substituent did not seem to affect the enantioselectivity. 

The reaction of phenyl-1,2-propadiene with iodine bromide in MeOH afforded a 100% yield of 2-iodo-3-phenyl-3-methoxy-l-propene whereas the reaction in CS2 at 0°C provided a l 4mixture of 2-iodo-3-phenyl-3-bromo-l-propene and l-phenyl-2-iodo-3-bromo-l-propene [16]. The corresponding chlorination shows a lower regios-... 

Due to electron withdrawing effect of nitro group and electron releasing effect of methoxy group. 11.20 (i) Hydration of Propene. 

To reduce to the active formula, see the zinc reduction as given in the reduction section, CPB, 16, 217 (1968). This reduction is specifically matched to 3-bromo-4,5-methylenedioxy-B-nitrostyrene and other highly substituted ring type styrenes and propenes. Zinc reductions carried out properly are very gentle and do not destroy delicate ring substituents, while some reductions do. Zinc reductions can reduce any nitrostyrene or propenes, but some of these compounds must use the zinc reduction. Which compounds Compounds with lots of ring substituents, like 2,5-dimethoxymethylenedioxy, 3-methoxy-4-0-carbethoxy, etc. This is not to say that some of the other reductions are not capable of gentle reductions. 

Ethyl vinyl ether 19a and methyl vinyl ether 19b are metalated by tert-butyllithium at the oxygen-adjacent methine site. -Alkyl groups retard the reaction substantially. Thus, l-methoxy-2-methyl-2-propene was found to be inert toward all... 

Another cycloaddition to an a,(3-unsaturated compound involves the reaction of nitrile oxides with 3-methoxy- or 3-methylthio-1 -phenyl-2-propene-1 -one (Scheme 6.18) (133,134). The isoxazoles that are isolated are considered to arise from the respective intermediate isoxazolines by subsequent elimination of methanol or methanethiol. The regioselectivity observed was attributed to the presence of substituents with strong electron-donating ability, and this was accommodated in terms of the FMO theory (133,134). 

Carbonyl-substituted nitrones are formed as mixture of (E)- and (Z)-stereo-isomers. By coordination to a Lewis acid, the (Z)-isomers are expected to be more stabilized due to tight complexation. Thus, a 2.8 1 ( /Z)-mixture of A -(methoxy-carbonylmethylene)methylamine A -oxide isomerizes to the (Z)-isomer in the presence of MgBr2-Et20 and undergoes a regio- and exo-selective cycloaddition reaction to 2-propen-l-ol to give the isoxazolidine-5-methanol as a single product... 

Asymmetric synthesis of 3-phcnylalkanaIs was realized by deprotonation of 2-methoxy-2-phenyl-l-[(T )-3-phenyl-2-propenyloxy]propane with potassium diisopropylamide (K.DA), followed by alkylation. The starting material is derived from ( )-3-bromo-l-phenyl-l-propene and (R)-2-methoxy-2-phenyl-l-propanol2. Alkylation occurred exclusively at the 3-position of... 

Umsetzung mit 1-(4-Methoxy-pheny])-propen zu 3-Methoxycarbonyl-5-(4-methoxy-phenyl)-4-me-thyl-4,5-dihydro-l, 2-oxazol. 

Coniferyl alcohol [4-hydroxy-3-methoxy-cinnamyl alcohol, 3-(4-hydroxy-3-methoxyphenyl)-2-propen-l-ol] [458-35-5] M 180.2, m 73-75°, 73-75°, b 163-165°/3mm. It is soluble in EtOH and insoluble in H2O. It can be recrystd from EtOH and distd in a vacuum. It polymerises in dilute acid. The benzoyl derivative has m 95-96° (from pet ether), and the tosylate has m 66°. [derivatives Freudenberg and Achtzehn B 88 10 1955, UV Herzog and HillmerR64 1288 1931. ... 

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