Prolonged ketosis

It is important to note that prolonged ketosis/acidosis can be dangerous or even fatal. One reason is that tbe excess urination could produce a secondary mineral imbalance, and tbis is dangerous, especially if one has a weak heart. Medically supervised diets try to avoid a true ketotic state, and people on such a limited-calorie diet should be under constant physician care. You can tell that you are in extreme ketosis by the metallic taste (acetone breath) in your mouth when you get up in the morning. 

Alanine Pyruvate/lactate defects Hyperammonemias Fasting Prolonged fasting, ketosis... 

Uloodglucose eoiicenlration. This will be maintained even in the face of prolonged starvation. Ketosis develops during starvation and carbohydrate deficiency. Hyperglycacmia is frequently encountered as part of the metabolic response to injury. 

The level of total ketone bodies in Lofata Burne s blood greatly exceeds normal fasting levels and the mild ketosis produced during exercise. In a person on a normal mealtime schedule, total blood ketone bodies rarely exceed 0.2 mM. During prolonged fasting, they may rise to 4 to 5 mM. Levels above 7 mM are considered evidence of ketoacidosis, because the acid produced must reach this level to exceed the bicarbonate buffer system in the blood and compensatory respiration (Kussmaul s respiration) (see Chapter 4). 

Two of the ketone bodies are acids, and their accumulation in the blood as ketosis worsens results in a condition of acidosis called ketoacidosis because it is caused by ketone bodies in the blood. If ketoacidosis is not controlled, the person becomes severely dehydrated because the kidneys excrete excessive amounts of water in response to low blood pH. Prolonged ketoacidosis leads to general debiUtation, coma, and even death. 

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