Progressive massive fibrosis PMF

Simple CWP often occurs concomitantly with chronic bronchitis and emphysema. Although CWP is associated with several respiratory impairments, it is not associated with shortened life span the importance of this benign condition is the fact that it is a precursor of progressive massive fibrosis (PMF). However, simple CWP does not progress in the absence of further exposure. 

Chronic bronchitis, pneumoconiosis, obstructive lung disease, focal emphysema, progressive massive fibrosis (PMF), coal workers pneumoconiosis (CWP), siUcosis Acute bronchospasm, pneumonitis, chronic exposure leads to Itmg fibrosis, progressive massive fibrosis (PMF), coal workers pneumoconiosis (CWP), silicosis Ocular and upper airway irritation, bronchospasm in severe exposure, contact dermatitis... 

Progressive Massive Fibrosis PMF or complicated CWP typically appears on a background of severe simple CWP. PMF lesions are most commonly... 

Fig.5.10a,b. A 68-year-old retired construction site worker, a Thin-section CT scan through the upper lobes shows bilateral progressive massive fibrosis (PMF) with surrounding paracicatricial emphysema, b Thin-section CT scan through the lower lobes shows confluent centrilobular emphysema (asterisks) in the right lower lobes and bullae in the left lower lobe (arrows)... 

CWP can be divided into a simple form with multiple small rounded pulmonary nodules and a complicated form with large masses, also called progressive massive fibrosis (PMF). The complication occurs in about 30% of patients who have diffuse bilateral small opacities and may develop after exposure to coal dust has ceased and may progress in the absence of further exposure (Morgan 1984). 

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