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Product design transdermal formulations

Preparations for cutaneous (or dermal) application may be used for local treatment as well as for transdermal administration with a systemic effect. The chapter focuses on preparations with a local effect and on design of formulation and method of preparation of those prepared in pharmacies. The interaction between skin, active substance and base, the anatomy of the skin and biopharmaceutical aspects of cutaneous preparations are discussed as well as the therapeutic effect of the base. Because of the important role of the pharmacist in prescription assessment some recommendations for the communication with the physician are given. One aspect is how to proceed with a request for the mixing of two licensed medicines or for the addition of an active substance or an excipient to a licensed product. The formulation design is generally following the several phases of the multicomponent preparations. Based on the... [Pg.229]

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See also in sourсe #XX -- [ Pg.215 , Pg.216 ]



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