Process Development Issues

Micromrxers provide very fast mixing, down to milliseconds or even below [9, 26]. The concentration profiles are uniform and there is good agreement between experiment and theory, which may make process development more predictable. Results at the laboratory scale may be maintained throughout the scale-out steps, since the fluid dynamics are not changed or at least shift by analogy in a known manner. This is particularly valid for very fast precipitations such as with Yellow 12 manufacture. Here, the seed formation and agglomeration process is impacted 

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Innovation - advocates and opponents origin from microtechnology list of microfabrication techniques selectivity and efficiency as main driver for industrial implementation special properties and general advantages of micro reactors process-development issues BASF investigations on liquid/liquid and gas-phase reactions micro reactors as ideal measuring tools production in micro reactors as exception, the rule will be transfer to mm-sized channels [111],... 

Knowing these shortcomings, the contents were grouped in sections on industrial mission statements, laboratory process development, pilot plants, and chemical production. For the process development issue papers were also considered with industrial coauthors, assuming that the work was (partly) done under industrial perspective and reflects fields of interest and activity of industry. 

Since the initial development started with the robust PolyMUMPS process in a commercial MEMS foundry, the modifications were straightforward and the product development could focus on design variations rather than process development issues. 

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