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Probing Gene Expression

LUMINESCENT DNA PROBE, GENE EXPRESSION REPORTER GENE ASSAYS... [Pg.517]

DNA microarrays, or DNA chips consist of thousands of individual DNA sequences arrayed at a high density on a single matrix, usually glass slides or quartz wafers, but sometimes on nylon substrates. Probes with known identity are used to determine complementary binding, thus allowing the analysis of gene expression, DNA sequence variation or protein levels in a highly parallel format. [Pg.526]

Pennie WD. Use of cDNA microarrays to probe and understand the toxicological consequences of altered gene expression. Toxicol Lett 2000 112-113 473-477. [Pg.125]


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