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Privileged building blocks

Privileged building blocks in chemo-differentiating ABB MCRs (reactions introducing into the final product one molecule of component A and two molecules of component B) 07CSR484. [Pg.18]

Isoxazoles are privileged aromatic heterocycles due to their wide spectrum of biological activities and their use as versatile building blocks in organic synthesis. Recent progress in the field of transition-metal-catalyzed cross-coupling reactions on isoxazole systems has been summarized and discussed <06EJO3283>. [Pg.288]

Rational Selection of Building Blocks Based on Privileged Structural Motifs... [Pg.288]

Scaffold proposals were collected and reviewed according to privileged ion channel motifs, chemical feasibility, and fit to our multiple pharmacophores. Building block selection, virtual library design, and filtering yielded small virtual libraries suitable for automated solution-phase synthesis. All synthesized compounds were finally purified and characterized prior to addition to our focused library. [Pg.236]

See other pages where Privileged building blocks is mentioned: [Pg.53]    [Pg.55]    [Pg.305]    [Pg.305]    [Pg.53]    [Pg.64]    [Pg.290]    [Pg.81]    [Pg.443]    [Pg.53]    [Pg.55]    [Pg.305]    [Pg.305]    [Pg.53]    [Pg.64]    [Pg.290]    [Pg.81]    [Pg.443]    [Pg.298]    [Pg.344]    [Pg.48]    [Pg.288]    [Pg.291]    [Pg.300]    [Pg.300]    [Pg.301]    [Pg.304]    [Pg.304]    [Pg.10]    [Pg.148]    [Pg.274]    [Pg.62]    [Pg.62]    [Pg.67]    [Pg.108]    [Pg.5]    [Pg.28]    [Pg.47]    [Pg.48]    [Pg.32]    [Pg.155]    [Pg.161]    [Pg.366]    [Pg.368]    [Pg.17]   
See also in sourсe #XX -- [ Pg.161 ]



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