Preparations of Adrenocortical Steroids and Their Synthetic Analogs

Preparations of Adrenocortical Steroids and Their Synthetic Analogs 

Nonproprietary and Proprietary Names Oral Forms Injectable Forms 

Dexamethasone acetate (Decadron-LA, others) 0.5 mg/0.5 mL (soln.) 8, 16 mg/mL (susp.) 

ACTH stimulates adrenal cortex to produce and secrete adrenocortical hormones (e.g., corticosteroids, glucocor- 

Agents that inhibit steps in the steroidogenic pathway and thus alter the biosynthesis of adrenocortical steroids are discussed, as are synthetic steroids that inhibit glucocorticoid action. The effects of corticosteroids are numerous and widespread, and include alterations in carbohydrate, protein, and lipid metabolism maintenance of fluid and electrolyte balance and preservation of normal function of the cardiovascular system, the immune system, the kidney, skeletal muscle, the endocrine system, and the nervous system. 

---