Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Practical quantitation limit

The MDL and practical quantitation limit (PQL) should be appropriate for the objectives of the analysis. MDL refers to the minimum concentration of the compound of interest that can be measured and reported with a specified confidence (99% probability) that the concentration is above zero. The registrants must provide or develop an analytical method for water for the parent pesticide and its degradates that has an MDL of 0.01% of the label application rate (calculated as the average concentration in the top six inches of soil), or 0.05 pgL , whichever is lower. PQL refers to the lowest concentration at which the laboratory can confidently quantify the concentration of the compound of interest. The study authors must report all samples with concentrations above the MDL as detections, including those below the PQL in which the concentration cannot be quantified. In addition, the study authors must provide sample equations to demonstrate how the PQL was calculated. [Pg.612]

Municipal Solid Waste Landfills Appendix II - List of Hazardous Inorganic and Organic Constituents 0.1-20 pg/L (Practical Quantitation Limits for 2 Methods) 40 CFR 258 EPA 1991b... [Pg.154]

The next step is to determine the practical detection limit (pDL) based on the signal-to-noise ratio at the lowest level at which the analyst can get the HPLC system to function reproducibly on injections of a standard at a known concentration (S/N ratio of 3 1 is a rule of thumb). Then the practical quantitation limit (pQL) is determined usually at a level 2-5 times the pDL and the repeatability of the standard at this level is determined. This pQL usually results in analyte concentrations of nanograms or micrograms per milliliter. The repeatability of a 1.0 pg/mL clarithromycin standard preparation is shown in Table 2. ... [Pg.403]

The limit of quantitation is the minimum concentration of an analyte in a specific matrix that can be determined above the method detection limit and within specified bias and precision limits under routine operating conditions (EPA, 1998a). The limit of quantitation is often referred to as the practical quantitation limit (PQL). The concept of PQL is discussed in Chapter 4.5.1. [Pg.46]

Estimated quantitation limit or practical quantitation limit... [Pg.241]

The terms estimated quantitation limit (EQL) and practical quantitation limit describe the limit of quantitation, another secondary data quality indicator. These terms are used interchangeably. In fact, the common term used by the laboratories is the PQL. The EPA, however, prefers to use the term EQL and defines it as follows The estimated quantitation limit EQL) is the lowest concentration that can be reliably achieved within specified limits of precision and accuracy during routine laboratory operating conditions (EPA, 1996a). The PQL is defined similarly (EPA, 1985). [Pg.241]

Step 2—Verify methods, analytes, and practical quantitation limits... [Pg.272]

IRIS = Integrated Risk Information System MCL = maximum contaminant level MCLG = maximum contaminant level goal NIOSH = National Institute for Occupational Safety and Health OEL = occupational exposure level OSHA = Occupational Safety and Health Administration PEL = permissible exposure limit PQL = practical quantitation limits RCRA= Resource Conservation and Recovery Act REL = recommended exposure limit ... [Pg.244]

For a known or probable carcinogen, (EPA Class A or B), the MCLG is set at zero (i.e., no amount of chemical is acceptable). Because no analytical methods can measure zero, however, the MCL is based on the lowest concentration that can be measured on a routine basis. This is known as the practical quantitation limit (PQL). Thus, it is obvious that for known or probable carcinogens, the MCL is not guaranteed to be a safe level but instead is the lowest measurable level. [Pg.43]

Partide Beam LC/MS is Suitable for Quantitative and Qualitative Analysis of Target Compounds. PB/LC/MS is effective both as a qualitative and quantitative method for a wide range of chemical classes. Complete calibration curves and practical quantitation limits have been produced using... [Pg.201]

Table I. Practical quantitation limits (PQL, ng injected), correlation coefficients (R2 and quadratic regression parameters (a and b) of 21 compounds with electron impact, and positive and negative chemical ionization (methane) Particle Beam mass spectrometry, direct flow injection with full scan mode... Table I. Practical quantitation limits (PQL, ng injected), correlation coefficients (R2 and quadratic regression parameters (a and b) of 21 compounds with electron impact, and positive and negative chemical ionization (methane) Particle Beam mass spectrometry, direct flow injection with full scan mode...
PQL practical quantitation limit this PQL is an average value for PCB congeners. [Pg.698]

PEL = permissible exposure limit POL = practical quantitation limit RAC = reference air concentration ... [Pg.152]

Figure 2.5 provides a graphical view of the terms used to define the decision limit, Xc and detection limit, x. The decision limit, x, is a specific concentration level for a targeted analyte above which one may decide whether or not the result of analytical measurement indicated detection. The detection limit, x j, is a specific concentration level for a targeted analyte above which one may rely upon to lead to detection. A third limit, known as a determination limit, or using more recent jargon from the EPA, the practical quantitation limit, is a specific concentration at which... [Pg.46]

Practical quantitation limit (PQL) The lowest level that can be reliably achieved within specified limits of precision and accuracy during routine laboratory operating conditions. [Pg.596]

Quantitation limit The minimum concentration of a compound that can be reliably quantified very dependent on the sample matrix. See Practical quantitation limit. [Pg.597]

Method detection limit (MDL) and practical quantitation limit (PQL) for current reference methods are adequate for typical screening or survey (epidemiological) and medical diagnostic purposes. [Pg.293]

Pb exposure appears to produce neurotoxic risk in children without an empirically observed threshold any threshold would be between 0 and 2—3 xg/dl PbB, approaching practical quantitation limits environmental Pb is still regulated as a threshold toxicant rather than as a categorical nonthreshold toxic, for example, genotoxic carcinogens... [Pg.491]

For the most part, the substances determined as part of waste analysis, the analytes, are measured by techniques that are used for the determination of the same analytes in water and, to a lesser extent, in air. However, the preparation techniques that must be employed for waste analysis are usually more complex than those used for the same analytes in water. This is because the matrices in which the waste analytes are contained are usually relatively complicated, which makes it difficult to recover all the analytes from the waste and which introduces interfering substances. As a result, the lower limits at which substances can be measured in wastes (a parameter known as the practical quantitation limit) are usually significantly higher than in water. [Pg.526]


See other pages where Practical quantitation limit is mentioned: [Pg.268]    [Pg.408]    [Pg.349]    [Pg.347]    [Pg.198]    [Pg.276]    [Pg.315]    [Pg.180]    [Pg.47]    [Pg.53]    [Pg.423]   
See also in sourсe #XX -- [ Pg.612 ]




SEARCH



Quantitative limitations

© 2024 chempedia.info