Potassium lozenge

GRAS listed. Accepted as a food additive in Europe (the E number E501 refers to potassium carbonates). Included in nonparenteral medicines licensed in the UK and USA (chewable tablets effervescent granules effervescent tablets lozenges oral granules oral suspensions). Included in the Canadian List of Acceptable Non-medicinal Ingredients. 

The method given under Compound Lozenge of Bismuth is clearly applicable to this preparation, except that there is no necessity to ignite in the determination of calcium and magnesium. The present B.P.C. method is based upon precipitation of the bismuth with potassium iodide and determination of total and soluble alkali. 

Lozenge of Potassium Chlorate, B.P,C. Contains 2 grains of potassium chlorate in a base of sugar and acacia. 

A formalin or nitrite reduction method may be used with advantage for the determination of chlorate in this lozenge. Standard mixtures of potassium chlorate with sugar and acacia have given theoretical yields of potassium chlorate by the following method ... 

Dissolve the equivalent of one lozenge in 10 ml of hot water. Cool, add 25 ml of O IN silver nitrate, 10 ml of dilute nitric acid and 5 ml of formaldehyde solution. Heat just to boiling and leave on a water-bath until the precipitate has coagulated. Filter, wash the precipitate and titrate the filtrate and washings with O IN potassium thiocyanate, using iron alum as indicator. 1 ml 0 1 N AgNOa = 0 01226 g KCIO3. 

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