Potassium heptylate

Potassium Heptylate gave besides dodecane, C H, a small quantity of an unsaturated hydrocarbon, probably octylene, C,H . 

To a N2 covered suspension of 0.29 g (7.57 mmol) of LiAIH4 in 10 ml of THF cooled in an ice bath is added a solution of 1.0 g (2.52 mmol) of N-ethyl-N-heptyl-y-oxo-4-[methylsulfonyl)amino]benzenebutanamide in 10 ml of THF over 6 min. The ice bath is then removed and the mixture heated at reflux for 27 h and then stirred at room temperature for 2 days. The mixture is cooled in an ice bath and there is added dropwise 10 ml of aqueous sodium potassium tartrate followed by EtOAc and H20 to keep the mixture fluid. 

On electrolyzing a concentrated solution of potassium n-heptylate, Rohland4 obtained, besides dodecane, Ci2H26, a small quantity of a mixture of unsaturated hydrocarbons of the series CJAzn boiling at 145°. 

Heptyl bromide was not hydrogenolyzed whatsoever, even in the presence of potassium acetate, while phenethyl bromide and 3-phenylpropyl bromide were hydo-genolyzed at considerable rates with addition of the base. Ethyl 3-bromopropionate, which resisted hydrogenolysis in neutral alcohol, as mentioned above, was hydrogenolyzed in the presence of the base, although at a slow rate. It is seen that the bomine located at the a-position is markedly activated by electron-withdrawing benzoyl and ethoxycarbonyl groups. 

The parent compound, perhydropyrrolo[l,2-a]pyrimidine (428), is obtained by the reaction between 4-chlorobutanal and 1,3-diaminopropane in the presence of potassium carbinate (83TLI559). A study of ring-chain tautomerism in such systems shows that in neutral aqueous solutions 428 predominates [84ACS(B)526]. 6-Propyl and 6-heptyl derivatives (430) were prepared by reduction of429 with LiAIH4. Hydroxyethylation of 430 with 50% excess ethylene oxide gives rise to 431 (76URP527433). 

To a cold (0 C), stirred suspension of potassium -cyclopentadienyldicarbonylferrate (2.00 g, 9.6 mmol) in THE (80 mL) was added dropwise a solution of 7-chlorobicyclo[4.1.0]heptyl-7-carboxylic acid chloride (3.50g, 16.2mmol) in THE (30mL). This mixture was allowed to stir for 30 min at 0°C followed by 3 h at rt. The reaction mixture was then transferred to a 100-mL round-bottom flask containing alumina (25 g) followed by removal of the solvent in vacuo. The reaction product coated on the alumina was chromatographed on an alumina column (hexane/CH2Cl2 80 20). A red band was first collected which was bis[(dicarbonylcyclopentdienyl)iron]. This was followed immediately by a yellow band. Removal of the solvent in vacuo gave 0.498 g (17%) of the product. 

Heptanoic Add, Enanthic acid oenanthic add oenanthylic acid n-heptoic add n-heptylic add. C,Hl40, mol wt 130.18. C 64.58%, H 10.84%, O 24.58%. CHj-(CHj)jCOOH. Found in the various fusel oils in appredable amounts. Has been observed in randd oils. Prepd by the oxidation of heptaldehyde with potassium permanganate in dil sulfuric add Ruhoff, Org. Syn. coll. voL II, 3]5 (1943). 

For the preparation of heptyl /7-nitrophenyl ether, potassium />-nitrophenoxide (20 g) was boiled under reflux, with rapid stirring, with heptyl bromide (25 g) and cyclopentanone (60 g). Formation of a thick slurry of potassium bromide began in 30 min and the reaction was complete in 2.5 h. After cooling, the mixture was taken up in ether, shaken with sodium hydroxide solution, and worked up as usual. The ether was formed in 89 % yield. Most of the cyclopentanone is recovered. 

Aliphatic and aromatic aldehydes react with carbon tetrabromide and triphenylphosphine to yield 1,1-dibromoalkenes 156, which are converted into alkynes 157 by the action of butyllithium or lithium amalgam. A convenient modification of the second step is the use of magnesium metal in boiling THF. 1-Chloro-l-alkynes 159 (R = Bu, hexyl, heptyl etc.) are produced from aldehydes and carbon tetrachloride/triphenylphosphine/magnesium, followed by dehydrochlorination of the products 158 with potassium hydroxide in the presence of the phase-transfer agent Aliquat 336. ... 

Coriander (Coriandrum sativum) oil Cupric sulfate anhydrous Dehydroacetic acid Dimethyl dicarbonate Disodium EDTA Edetic acid Erythorbic acid Ethyl vanillate Ferulic acid Formic acid Fructose Fumaric acid Glucose oxidase Guaiac gum Heptyl paraben Hexamethylenetetramine 4-Hydroxymethyl-2,6-di-t-butylphenol Isobutylparaben Isopropyl citrate Isopropylparaben Lactic acid Methyl paraben Myristalkonium chloride Natamycin Nisin o-Phenylphenol Potassium acetate Potassium bisulfite Potassium butyl paraben Potassium diacetate... 

Zirconium potassium hexafluoride 16925-39-6 Calcium silicofluoride 16930-96-4 Hexyl tiglate 16930-99-7 Heptyl crotonate 16940-66-2 Borino ... 

Obtained by alkaline degradation of various siphuUn derivatives with potassium hydroxide in refluxing methanol [3657], The siphulin (an homoflavone) 7-hydroxy-5-heptyl-2-[3, 5 -dihydroxy-2-carboxybenzyl]chroman-4-one (m.p. 180°) [3658] is a constituent of the North Scandinavican lichen siphula ceratites (Wahlenberg) Fr. 

Preparation by reaction of heptyl bromide with 5-allyl-2,4-dihydroxyacetophenone in the presence of potassium carbonate and potassium iodide in refluxing methyl ethyl ketone (77%) [2671], (40%) [2678,2679]. 

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