Postherpetic neuralgia gabapentin

Postherpetic neuralgia In adults with postherpetic neuralgia, gabapentin therapy may be initiated as a single 300 mg dose on day 1,600 mg/day on day 2 (divided... 

For postherpetic neuralgia, gabapentin can decrease concomitant opiate use... 

Response data for two studies were submitted to the FDA for approval for the treatment of postherpetic neuralgia (PHN). Both studies were randomized, double-blind, placebo-controlled, multicenter studies that evaluated the safety and efficacy of gabapentin administered orally three times a day, compared with placebo. In both studies, the patients were titrated to their final-treatment dose by the end of either week... 

Gabapentin, an anticonvulsant that stimulates gamma-aminobutyric acid (GABA) receptors, is used as an adjunctive therapy in treattnent of partial seizures with or without secondary generalization in patients older than 12 years of age with epilepsy adjunctive therapy for partial seizures in children 3 to 12 years of age and for management of postherpetic neuralgia in adults (see Figure 53). 

Wallace MS, Irving G, Cowles VE. Gabapentin extended-release tablets for the treatment of patients with postherpetic neuralgia a randomized, double-blind, pfacebo-controlled, multicentre study. Clin Drug Investig 2010 30(11) 765-76. 

Rice AS, Maton S. Postherpetic Neuralgia Study Group. Gabapentin in postherpetic neuralgia a randomized, double blind, placebo controlled study. Pflm2001 94(2) 215-224. 

Rowbotham M, Harden N, Stacey B, et al. Gabapentin for the treatment of postherpetic neuralgia a randomized controlled trial. JAMA 1998 280(21) 1837-1842. 

O Connor AB, Noyes K, Holloway RG. A cost-effectiveness comparison of desipramine, gabapentin, and pregabalm for treating postherpetic neuralgia. / Am Geriatr Soc 2007 55(8) 1176-1184. 

Irving G. Once-daily gastroretentive gabapentin for the management of postherpetic neuralgia an update for clinicians. Ther Adv Chronic... 

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