Postexposure delay

The stability of the exposed latent image before PEB (during postexposure delay) against airborne contaminants is still an important issue to consider. 

Signs and Symptoms Flu-like symptoms with fever, headache, drowsiness, cough, abdominal pain, nausea, vomiting, weakness, problems with swallowing, and blurred vision that may progress to encephalitis with drowsiness, disorientation, severe hypertension, rapid heart rate (tachycardia), very high temperature, convulsions, and coma. Encephalitis may be delayed up to 4 months postexposure. Nipah virus is also known to cause relapse encephalitis. 

There is evidence that ozone has a delayed effect on elastic behavior. Excised lungs of rabbits that were unilaterally exposed to ozone at 1.0 ppm for 3 h and then allowed to breathe ambient air for up to 2 weeks showed a depression in the volume-pressure curves. This change was present during most of the postexposure test period. The mechanism underlying this response was not determined. ... 

Shinohara et reported that up to 10 h of postexposure light did not affect the response of tobacco (H-mutant) to ozone. Davis and WoocT delayed symptom development in Virginia pine when the plants were held in the dark for extended periods after ozone exposure. However, the final severity of response was unchanged. 

Tetanus Tetanus immune globulin Postexposure prophylaxis 250 units IM. For severe wounds or when there has been a delay in administration, 500 units is recommended. Treatment of tetanus and postexposure prophylaxis of nonclean, nonminor wounds in inadequately immunized persons (less than two doses of tetanus toxoid or less than three doses if wound is more than 24 hours old). 

Postexposure deaths were also reduced in the animals exposed to the combustion products from the Cu and Cu20-treated FPU foams in the small-scale tests. These delayed postexposure deaths have not been observed in animals exposed to combustion products from flexible polyurethane foams decomposed in large-scale room fire tests. The specific cause of these postexposure deaths is not known. 

Topcoats also provide a protective function against airborne molecular contaminants such as amines. Figure 13.53 shows PEB delay stabilty of up to 15 minutes obtained on a resist film protected with a topcoat. Following the indicated PEB delay times, the resist film was postexposure baked and developed. Even after 15 minutes, the CD values of the 80-nm and 90-nm lines/space features remained remarkably stable. This is considerably better performance than that achieved when topcoat is not used. 

Estimates of the impact of the delay in postexposure prophylaxis or treatment on survival are not known. For gastrointe.stinal anthrax, the case-fatality rate is estimated to be 2.5%-60% and the effect of early antibiotic treatment on that case-fatality rate is not defined. 

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