Pomelo juice

In addition to GFJ, orange juice and pomelo juice also have been shown to inhibit the activity of P-gp in vitro (73). Flavones from orange juice have been shown to be more potent than compounds from grapefruit in the inhibition of P-gp (97). 

Grapefruit juice and pomelo juice, but not cranberry or orange juice, can increase the bioavailability of ciclosporin. 

A study in 12 healthy subjects given a single 200-mg dose of ciclosporin found that pomelo juice significantly increased the AUC and maximum level of ciclosporin by about 19% and 12%, respectively, whereas cranberry juice did not have any significant effects on ciclosporin pharmacokinetics. ... 

Grenier J, Fradette C, Morelli G, Merritt GJ, Vranderick M, Ducharme MP. Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine inhumans. CUnPharmacol Ther (2006) 79, 255-62. 

Grapefruit juice can markediy increase the serum levels of tacrolimus. Pomelo may interact similarly. 

A study of cranberry juice (240 ml) and cyclosporine indicated that a single dose of cranberry juice had no effect on cyclosporine metabolism, whereas a single dose of a citrus fruit juice (pomelo) had a significant effect (Grenier et al. 2006). 

Pomelo Citrus maxima Rutaceae Fresh,juice... 

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