Polysporin - Polymyxin

Bacitracin Polymyxin B, Topical (Polysporin) Bacitracin, Neomycin, Polymyxin B, Topical (Neosporin Ointment) Bacitracin, Neomycin, Pol5rm5 xm B, Hydrocortisone, Topical (Cortisporin)... 

Bacitracin zinc polymyxin B sulfate Polysporin Propylene glycol, sorbitan sesquioleate, and white petrolatum... 

Alternatively, antibiotics such as trimethoprim-polymyxin B (Polytrim), gentamicin, or tobramycin solution, instilled as one drop four times daily for 5 to 7 days, or prior generation fluoroquinolones such as ciprofloxacin, ofloxacin, or levofloxacin, dosed four times daily for 5 to 7 days, may be prescribed. Bacitracin-polymyxin B (Polysporin), erythromycin, gentamicin, tobramycin, or ciprofloxacin ointment may be used at bedtime as supplemental therapy or four times daily in children or other patients who are not comfortable with eyedrops. 

Bacitracin is bactericidal for most gram-positive organisms, especially Staphylococcus and Streptococcus species. It is particularly useful when combined with polymyxin B in an ophthalmic ointment. Bacitracin-polymyxin B ointment (Polysporin) provides broad-spectrum antibacterial activity for patients who require nighttime therapy or who are not comfortable with eyedrops. Bacitracin-polymyxin B ointment is particularly effective in the pediatric population because of the high incidence of Streptococcus infection.The usual dose frequency is three to four times daily.Although adverse events are rare, hypersensitivity reactions can occur. Additionally, bacitracin can sometimes be uncomfortable. 

Superficial (first-degree bum) The epidermis is red, painful, dry, and no blisters (i.e., sun bum). Superficial bums are treated by removing clothing at the bum site and placing a cold wet compress on the bum site to constrict blood vessels, reducing swelling and pain. Superficial bums should be treated with antibiotics such as Bacitracin with polymyxin B (Polysporin) and similar over-the-counter (OTC) antibiotics. 

Don t apply greasy ointments, butter, or a dressing to the burned area. This inhibits heat loss and increases tissue damage. Bacitracin with polymyxin B (Polysporin) and similar over-the-counter antibiotics should be used. 

Trade names Aerosporin, Cortisporin, Neo-Polycin, Neosporin, Octicair, Ophthocort, Otobiotic Otic, Otocort, Polymyxin B, Polysporin, Pyocidin-Otic, Terramycin, Topisporin, Tri-Thalmic Use Antibacterial HPLC ... 

Knowles SR, Shear NH (1995) Anaphylaxis from bacitracin and polymyxin B (Polysporin) ointment. Int J Dermatol... 

In conclusion, evidence exists for the topical use of mupirocin, polysporin B, and to a lesser degree PVI for CLABSI prevention. The potential for mupirocin resistance development has to be considered. Currently, while gramicidin is not available in the US, a similar preparation in the form of bacitracin/neomycin/ polymyxin B is commonly used. 

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