PolyQactic acid

S. E. M., and Tsuji, H., ed.], PolyQactic acid]. Synthesis, Structure, Properties, Processing, and Application, Wiley, New Jersey, Chapter 1, pp. 3-16. 

Ajioka, M., Enomoto, K., Suzuki, K., Yamaguchi, A. The basic properties of polyQactic acid) produced by the direct condensation polymerization of lactic acid. I. Environ. Polvm. Dearad.. 1995, 3, 225-234. 

Imnes, Bedo, D., Domjan, A., Shon, P., Vancso, G. J., Pukanszky B. (2013). Structure, properties and interfacial interactions in polyQactic acid)/ pol3nirethane blends prepared by reactive processing, Bun Po jjJ, 49(10), 3104-3113. 

PolyQactic acid] was discovered by Carothers at DuPont in 1932. Only a low-molecular-weight PLA could be produced by heating lactic acid under vacuum while removing the condensed water [1]. 

Yu, T., Ren, J., Gu, S., and Yang, M. (2010). Preparation and characterization of biodegradable polyQactic acid)-block-poly(c-caprolactone) multiblock copolymer. Polym Adv. TechnoL, 21,183-188. 

Aydin, M., Tozlu, T., Kemaloglu, S., Aytac, A., and Ozkoc, G. (2011). Effects of alkali treatment on the properties of short flax fiber-polyQactic acid) eco-composites.. 2/m2 Hljiajfl, 19,11-17. 

Yu, L., Petinakis, E., Dean, K. and Lie, H. (2010) PolyQactic acid)/starch blends, in Poly(Lactic Acid) Synthesis, Structures, Properties, Processing, and Applications (WUey Series on Polymer Engineering and Technology) (eds R. Auras, L.-T. Lim, S.E.M. Selke and H. Tsuji), John Wiley Sons, Inc., NJ, pp. 217-226. 

Electrospinning is applicable to a wide range of polymers like those used in conventional spinning, that is, polyolefine, polyamides, polyester, aramide, and acrylic, as well as biopolymers like proteins, DNA, and polypeptides, or others like electrically conducting, photonic and other polymers such as poly(ethylene oxide] (PEO], DNA, poly(acrylic acid] (PAA], polyQactic acid] (PEA], and also collagen, organics such as nylon, polyester, and acryl resin, and poly(vinyl alcohol] (PVA], polystyrene (PS], polyacrylonitrile (PAN], peptide, cellulose, etc. 

HCl-doped poly(aniline-co-3-aminobenzoic acid] (3ABA-PANI] copolymer and polyQactic acid] (PLA] blend were electrospun in the form of three-dimensional networks with a high degree of connectivity onto glass substrates. 

Polycarbonate blends with polyQactic acid) have been compatibilized through addition of bis(isocyanate), bis(carbodiimide), oxazoUne-f-PS, or epoxy resin (Wang et al. 2012e Mukawa et al. 2011). 

Wu et al. [129] prepared biodegradable polyQactic acid) (PLA)/organically modified montmorillonite (m-MMT) nanocomposites by solution blending, the most critical part of this process being the modification of the MMT. The MMT was first treated with hexadecyltrimethyl-ammonium bromide (CTAB) cations, and then modified with biocompatible and biodegradable chitosan. As the chemical similarity between m-MMT and PLA was improved, the m-MMT became well separated in the PLA matrix. 

To overcome the problem, they used controlled drug-delivery systems. With this we can deliver drugs in a constant, predetermined rate to the repair area only. The active molecule can be encapsulated with the polymer member and there can be slow release of the drug into the tissues. In few cases, the release of the molecule may be due to the diffusion of the pol mier matrix. PolyQactic acid) and polyfortho ester)s are degradable pol miers that are used for drug-delivery systems. 

Degradation rate of this copolymer is slower than other biodegradahle polymers such as poly(lactic acid) and polyQactic-co-glycolic acid), therefore suitable for use in implants (Hu et al. 2004). 

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