Polyneuritis diabetic

Chemical, biological, and pharmacological properties of lipoic acid as well as its therapeutic effects in several diseases (diabetes mellitus, liver cirrhosis, polyneuritis, etc.) are reviewed [198,199], It is evident from the chemical structures of LA and DHLA that only DHLA may be an efficient scavenger of all oxygen radicals, while LA should be active only in the reactions with highly reactive hydroxyl radicals. On the other hand, DHLA must be easily... 

Autoimmunity or chronic inflammation are now considered to be the basis of a large number of diseases including multiple sclerosis, polyneuritis, rheumatoid arthritis and type 1 diabetes mellitus. There is strong evidence that supplementation of the diet of patients suffering from rheumatoid arthritis with fish oil is beneficial. Studies on other conditions are in progress (see Calder, 2006). 

The complications of diabetes have now become classical. They include the development of cataracts, xanthelasmas, retinitis, generalized arteriosclerosis, increased sensitivity to infections, glomerular nephrosclerosis, polyneuritis, and delivery of abnormally large infants.. 

RCT, randomized controiied triai with positive resuits MA, metaanalysis of RCTs with positive resuits OA, osteoarthritis CLBP, chronic low back pain FMS, fibromyaigia syndrome Diabetic PN = diabetic peripheral neuropathy PHN, post-herpetic neuraigia Painfui polyneur, painful polyneuropathy n.t, not tested Neg., negative results in 2 1 RCT Contra, contradictory evidence. 

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