Polymethacrylamides, side-chain polymers

Blaschke et al. [54—56] synthesized polyacrylamide and polymethacrylamide containing chiral side chains. In order to make CSPs, these polymers were bonded to silica gel chemically [54-56]. The CSP obtained by /V-acrylol-(.S)-phenylalanine ethyl ester was commercialized by Merck Chemical Company by the trade name ChiraSpher. The racemic compounds resolved are those capable of forming hydrogen-bondings (i.e., amides, imides, carboxylic acids, and alcohols). It has been reported that nonpolar solvents like benzene and toluene individually or their mixtures were the best mobile phases. In addition to these CSPs, other amide CSPs were prepared and tested for the chiral resolution [57,58]. 

Side-Chain-Type Polymers. We synthesized two types of side-chain-type polymers, polymethacrylamide (7/) and polymethacrylate, both containing triphenylamine or tetraphenyldiamine as functional groups. As illustrated in Figure 3, hole transport in these polymers is due to hole movement along the triphenylamine moieties and hopping between chains. 

Synthetic polymers with amino acid side chains these have a synthetic backbone where amino acids and peptides are present as side chains. These materials show a polyelectrolytic and metal complexation behavior. Polymethacrylamides with glycylglycine and phenylalanine are a good example of such systems. 

These polymers consist of a synthetic polymer backbone onto which amino acids or peptides are grafted as side chains. Examples of materials with amino acids as side chains have been found to exhibit polyelectrolytic and metal complexation behaviour. Such systems include polymethacrylamides with glycylglycine and phenylalanine (Methenitis, 1994), as well as alanine, aspartic acid, asparagine, glutamic acid, and lysine (Morcellet-Sauvage, 1981 Morcellet, 1982 Lekchiri, 1987). 

A-substituted polymethacrylamides with alkylaldonamide side chains Phase diagram for the polymer with v = 10 and... 

A series of polyacrylamides and polymethacrylamides having different alkyl-, alkoxyalkyl- and hydroxyalkyl-groups in their side chain structure was prepared via free radical polymerization of N-substituted-acrylamides or -methacrylamides which have been synthesized from corresponding alkylamines and acryloyl chlorides. The solubility of these polymers in water is classified into three types depending on the side chain structures as l)soluble in water irrespective of temperature,2)soluble in cold water but insoluble at higher temperatures,3)insoluble into water at any temperatures. 

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