Polymer-based antimicrobials

Arora, S., Yadav, V., Kumar, P., Gupta, R., Kumar, D., 2013. Polymer based antimicrobial coatings as potential biomaterial a review. International Journal of Pharmaceutical Sciences Review and Research 23 (2), 279—290. Art. No. 46. 

The antimicrobial activity and durability of peroxide-cured rabber formulations containing silver-based antimicrobials are discussed in depth. 20 refs. (ACSd ubber Div.,160th Fall Technical Meeting, 16th-19th Oct.2001, Cleveland, Ohio) Articles from this journal can be requested for translation by subscribers to the Rapra produced International Polymer Science and Technology. 

A new class of antimicrobial polymers is described in which the microbiological activity is based on their special constitution, which comprises surface-located amino functional groups, and the three-dimensional stracture of the polymers. The antimicrobial efficacy is attributed only to the final polymer itself, not to leaching of low molec.wL additives or the initial monomers. The polymers are not soluble in water and do not leach from surfaces like low... 

Functionalised Antimicrobial Polymers Based on Poly(hydroxystyrene-co-methyl methacrylate) Derivatives... 

The use of polymeric ammonium salts and a sulfonic acid salt of sodium is an easy and efficient way of coating fabrics furthermore, employing the layer-by-layer (LbL) deposition technique can broaden the application of N-halamine biocides in other polar substances for use as antimicrobial coatings. Branched PEI, polypropylene (PP) and styrene maleic anhydride copolymers are a very good coating for food packaging materials, possibly due to the presence of both cationic- and N-halamine-forming structures. N-halamine cationic antimicrobial polymers based on (acrylamidopropyl)trimethylammonium chloride, PDDA chloride and poly(2-acrylamido-2-methylpropane sulfonic acid sodium salt) have been synthesised and coated onto cotton fabrics via an LbL deposition technique. 

The chemical modification of CS biopolymers via reductive amination, to yield alkylated CS derivatives, and further quaternisation result in very efficient antibacterial materials the degree of activity is correlated to the length of the alkyl chain and bacterial strain. The most active CS derivatives are more selective at killing bacteria than the quaternary ammonium disinfectants, cetylpyridinium chloride and benzalkonium chloride, and AMP. Vanillin can be used as a crosslinker of CS nsing this approach, functionalised antimicrobial polymers based on CS, vanillin. Tween 60 and so on may be easily prepared. Imino-CS biopolymer films, prepared by the acid condensation of the amino groups of CS with various aldehydes, can be used as functional biodynamic materials. 

Tripathi, S., Mehrotra, G. K., and Dutta, P. K. 2008b. Chitosan based antimicrobial films for food packaging applications, e-Polymers, no. 093,1-7. 

Among the many deals, only a few may be mentioned here. Arkema and Ciba Specialty Chemicals signed a global cooperation agreement enabling Ciba to distribute Arkema s Pebax permanent antistatic agents. They are polyether block amides intended for use in ABS, polystyrene and PVC. The two companies are also co-operating in research and development in the same area. Ciba has also become the exclusive distributor outside Asia of Kanebo Chemical s silver-based antimicrobial products for polymers. They are said to be effective, safe and heat-resistant to over 200 °C. 

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