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Polylactide-co-glycolide

Polylactide-co-glycolide co-polymers Lactic acid Glycolic acid [15]... [Pg.350]

Figure 13.8. Effects of route and sustained release formulation on the time course of human growth hormone concentration in plasma. Shown is the average time course of human growth hormone (hGH) in plasma after intravenous (0.02mg/kg) and subcutaneous (0.1 mg/kg) administration in humans. Arrows indicate weekly subcutaneous dosing of hGH in solution. A single dose of the same protein formulated in polylactide-co-glycolide (PLG) microspheres (0.75 mg/kg) given subcutaneously sustains human growth hormone levels in plasma for at least one month. Figure 13.8. Effects of route and sustained release formulation on the time course of human growth hormone concentration in plasma. Shown is the average time course of human growth hormone (hGH) in plasma after intravenous (0.02mg/kg) and subcutaneous (0.1 mg/kg) administration in humans. Arrows indicate weekly subcutaneous dosing of hGH in solution. A single dose of the same protein formulated in polylactide-co-glycolide (PLG) microspheres (0.75 mg/kg) given subcutaneously sustains human growth hormone levels in plasma for at least one month.
Singh, M., Fang, J.H., Kazzaz, J., Ugozzoli, M., Chesko, J., Malyala, P., Dhaliwal, R., Wei, R. et al. (2006) A modified process for preparing cationic polylactide-co-glycolide microparticles with adsorbed DNA. International Journal... [Pg.30]

Perugini, R, Genta, I., Pavanetto, F., Modena, T., Maculotti, K., and Conti, B. (2002), Evaluation of enzyme stability during preparation of polylactide-co-glycolide microspheres, J. Microencapsul., 19,591-602. [Pg.441]

Polylactide-co-glycolide (PLGA) microparticles releasing curcumin for 4 weeks after subcutaneous injection can be used as slow-release systems for cancer prevention (Figure 36.5). ... [Pg.749]

Dunne M, Bibby DC, Jones JC, Cndmore S. Encapsulation of protamine sulphate compacted DNA in polylactide and polylactide-co-glycolide microparticles. Journal of Controlled Release. September 19, 2003 92(l-2) 209-219. PnbMed PMID 14499198. [Pg.1022]

R. Dinarvand, N. Sepehri, S. Manoochehri, H. Rouhani, F. Atyabi, Polylactide-co-glycolide nanoparticles for controlled delivay of anticancer agents, Int. J. Nanomedicine 6 (2011) 877-895. [Pg.394]

Cell-culture studies have indicated that such structures promote cellular infiltration into the fibrillar network and can become densely populated in a reasonably short time. A number of natural and synthetic polymers have been successfully electrospun into fibrous scaffolds for the purpose collagen, elastin, gelatin, fibrinogen, polyglycolic acid, polylactic acid, polycaprolactone, polylactide-co-glycolide and polylactide-co-caprolac-tone. Recently published work indicates that an electrospun web formed... [Pg.227]

Dawson GF, Halbert GW (2000) The in vitro cell association of invasin coated polylactide-co-glycolide nanoparticles. Pharm Res 17 1420-1425... [Pg.196]

Ehrenfried, L.M., Patel, M.H., Cameron, R.E., 2008. The effect of tri-calcium phosphate (TCP) addition on the degradation of polylactide-co-glycolide (PLGA). s.l. Journal of Materials Science Materials in Medicine 19 (1), 459—466. [Pg.251]

Dunne M, Corrigan 1, Ramtoola Z. Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles. Biomaterials 2000 21(16) 1659-68. [Pg.260]

STUDY OF THE INITIAL STAGES OF DRUG RELEASE FROM A DEGRADABLE MATRIX OF POLYLACTIDE-CO-GLYCOLIDE... [Pg.52]

Journal of Microencapsulation 19, No. I. Jan./Feb. 2002, p.83-94 VANCOMYCIN RELEASE FROM POLYLACTIDE AND POLYLACTIDE-CO-GLYCOLIDE DISKS Ozalp Y OzdemirN Hasirci V Ankara,U ni versity... [Pg.81]


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See also in sourсe #XX -- [ Pg.243 , Pg.247 ]

See also in sourсe #XX -- [ Pg.626 ]

See also in sourсe #XX -- [ Pg.322 ]




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Glycolide

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